Global NGS Sample Preparation Market Size By Product (Reagents & Consumables, Workstations), By Workflow (DNA Fragmentation & Library Preparation, Target Enrichment), By Sample Type (DNA, RNA), By Application (Diagnostics, Drug Discovery), By End-User (Academic Institute & Clinical Research Institute, Hospital & Clinics), By Geographic Scope And Forecast

NGS Sample Preparation Market Size And Forecast

NGS Sample Preparation Market size was valued at USD 1.68 Billion in 2021 and is projected to reach USD 5.2 Billion by 2030 growing at a CAGR of 13.4% from 2023 to 2030.

What's fueling the growth of the NGS market? Well, it's a couple of thingscheaper sequencing technologies, and the fact that doctors are increasingly okay with using Next-Generation Sequencing (NGS) for diagnosis. But there's more! We're also seeing more genetic abnormalities cropping up in infectious and chronic diseases. Plus, NGS is becoming a big deal in cancer diagnosis and treatment. Want the inside scoop? The Global NGS Sample Preparation Market report takes a deep dive into all this. It really gives you the full picture, breaking down key segments, spotting the trends, highlighting what's driving growth, and identifying the roadblocks. It even looks at who's competing and the other important factors shaping the market.

Global NGS Sample Preparation Market Definition

Next-generation sequencing (NGS) sample preparation is a crucial step in genomics research and involves the transformation of biological samples into a format suitable for sequencing on NGS platforms. The NGS Sample Preparation Market offers a range of products and services to facilitate this process, ensuring accurate and high-quality sequencing data. The goal of NGS sample preparation is to generate high-quality sequencing data by properly preparing the biological sample for sequencing.

This involves breaking down the DNA or RNA into smaller fragments, adding adapters or barcodes to the fragments for identification, amplifying the fragments if necessary, and performing quality control checks to ensure the accuracy and reliability of the sequencing results. NGS sample preparation may also involve target enrichment techniques, which selectively capture specific genomic regions of interest for sequencing, allowing researchers to focus on particular genes or regions in the genome.

The NGS Sample Preparation Market offers a variety of products and services to support each of these steps. Numerous companies provide kits, reagents, and instruments specifically designed for DNA fragmentation, library preparation, target enrichment, and quality control in NGS workflows. These products aim to streamline the sample preparation process, enhance sequencing efficiency, and improve the overall quality of sequencing data.

The NGS Sample Preparation Market can be segmented based on product, workflow, sample type, application, and end user. The product segment includes reagents & consumables, workstations, and services. Reagents & consumables consist of kits and materials needed for sample preparation, while workstations involve instruments and automated systems. Services encompass specialized offerings like sequencing and data analysis.

The workflow segment comprises DNA fragmentation & library preparation, target enrichment, and quality control processes. The sample type focuses on DNA and RNA preparations. Applications include diagnostics, drug discovery, agricultural & animal research, and others. The end users are academic institutes & research institutes, hospitals & clinics, pharma & biotech companies, and others.

Global NGS Sample Preparation Market Overview

The increased efficiency of genotyping and preparation methods is one of the main factors driving the market for NGS sample preparation. Human whole genome sequencing has experienced exponential growth in recent years, setting new benchmarks for genotyping, particularly in bacterial infection outbreak investigations. NGS sample preparation has emerged as a leading technology for genotyping in such scenarios. Illumina devices are widely used for NGS sample preparation, but protocols from other major players like ThermoFisher and PerkinElmer are also available.

The efficiency of genotyping and preparation protocols in NGS sample preparation plays a vital role in accelerating research, outbreak investigations, and various applications in genomics. The continuous advancements in protocols and technologies contribute to the growth of the NGS Sample Preparation Market by providing researchers with improved tools and methodologies for efficient and high-quality sample preparation. The availability of alternative technologies is one of the major barriers to the market for NGS sample preparation.

While NGS has revolutionized genomic research and diagnostics, other techniques such as Sanger sequencing, antigen tests, polymerase chain reaction (PCR), and serological tests continue to be used for disease diagnosis. Sanger sequencing, which has been dominant in genomic research for the past two decades, has achieved significant milestones in genomics. Antigen tests are commonly employed to detect specific viral or bacterial antigens, providing rapid results. PCR is widely utilized for DNA amplification and detection of specific sequences.

Serological tests, on the other hand, detect antibodies in the blood and are used to determine the viral presence or antibody response to certain infections. These alternative technologies offer specific advantages, established protocols, and familiarity, which can limit the adoption and market growth of NGS sample preparation in certain applications and regions. However, the NGS Sample Preparation Market arises from the increasing collaborations and partnerships among key players. Major companies like Illumina, Thermo Fisher Scientific, and PerkinElmer are actively engaging in collaborations with research laboratories, academic institutes, hospitals, clinics, and other pharmaceutical and biotechnology companies.

These partnerships facilitate the introduction of new technologies, products, and research projects into the market. The collaborative efforts aim to address the evolving needs and challenges in NGS sample preparation, driving advancements and innovation. Additionally, these collaborations expand the reach and customer base for NGS sample preparation products and services. They enhance market penetration and offer avenues for joint research projects, resulting in the creation of unique value propositions and competitive advantages.

Global NGS Sample Preparation Market Segmentation Analysis

The Global NGS Sample Preparation Market is Segmented on the basis of Product, Workflow, Sample Type, Application, End-User, And Geography.

NGS Sample Preparation Market, By Product

• Reagents & Consumables
• Workstations
• Services

Based on Product, the market is segmented into Reagents & Consumables, Workstations, and Services. The workstation/instruments segment dominated the product and services segment of the NGS Sample Preparation Market. There is a growing demand for automation in NGS sample preparation workflows to enhance efficiency, reduce manual labor, and ensure consistency in the results. Workstations and instruments designed specifically for NGS sample preparation play a crucial role in automating various steps, such as DNA/RNA fragmentation, library preparation, and target enrichment. This automation enables higher throughput, minimizes human errors, and increases overall productivity.

NGS Sample Preparation Market, By Workflow

• DNA Fragmentation & Library Preparation
• Target Enrichment
• QC

When we look at how the work actually gets done—the workflow—we see the market divided into a few key areasDNA Fragmentation & Library Preparation, Target Enrichment, and QC. Right now, the library preparation part is really leading the way, holding the largest chunk of the market. What's interesting is that library prep often mixes both old-school manual techniques with newer automated methods to get those NGS libraries ready. This mix-and-match approach is great because it gives researchers a lot of wiggle room and fine-grained control. They can still handle the really crucial steps by hand, while letting the machines handle things like attaching barcoded molecular adaptors, end repair, and cleaning things up. This smart blend of manual and automated steps is why library preparation is so efficient and accurate, and it’s really fueling the segment's growth.

NGS Sample Preparation Market, By Sample Type

• DNA
• RNA

Based on Sample Type, the market is segmented into DNA and RNA. The DNA segment accounted for the largest share of the sample type segment of the NGS Sample Preparation Market. DNA-based analysis plays a crucial role in understanding the genetic basis of cancer. With the increasing prevalence of cancer cases worldwide, there is a growing demand for DNA sample preparation in NGS workflows. DNA sequencing enables the identification of genetic mutations, variations, and biomarkers associated with cancer, facilitating personalized treatment approaches and precision medicine.

NGS Sample Preparation Market, By Application

• Diagnostics
• Drug Discovery
• Agricultural & Animal Research
• Others

Based on Application, the market is segmented into Diagnostics, Drug Discovery, Agricultural & Animal research, and Others. The diagnostics segment has generated the highest revenue in the application segment of the NGS Sample Preparation Market. NGS-based diagnostics have proven to be highly effective in the early and accurate detection of infectious diseases. NGS sample preparation enables the identification and characterization of pathogens, including viruses, bacteria, and fungi, facilitating rapid and precise diagnosis for timely treatment and control of infectious diseases.

NGS Sample Preparation Market, By End-User

• Academic Institute & Clinical Research Institute
• Hospital & Clinics
• Pharma & Biotech companies
• Others

Okay, so who's using all this stuff? Well, the market's broken down by the end-useryou've got your Academic & Clinical Research Institutes, Hospitals & Clinics, big Pharma & Biotech companies, and then just, well, "Others." But the clinical research folks? They're really leading the charge, holding a pretty big chunk of the market. Why? A lot of it's because NGS is a total game-changer in cancer research. It's helped us find new genes related to cancer, understand how different tumors can be, and figure out the genetic tweaks that make tumors grow. Plus, there's been a surge in funding from government agencies, pushing NGS tech into clinical research labs. These government initiatives and grants? They're like fuel, really helping clinical research grow and making it easier to get samples ready for NGS in all sorts of clinical studies and trials.

NGS Sample Preparation Market, By Geography

• North America
• Europe
• Asia Pacific
• Latin America
• Middle East and Africa

When we look at the world, the NGS Sample Preparation Market is divided into places like North America, Europe, Asia Pacific, Latin America, and the Middle East & Africa. North America has really led the way, and we think it'll keep being a big player for a while. That's because governments and companies there are really pushing NGS with helpful programs and rules. This is making it easier for the NGS Sample Preparation Market to grow. People in North America are also starting to "get" how helpful NGS is, thanks to advancements in genomic medicine, so more are using it. You'll find researchers, doctors, and even big pharma companies using NGS tech more and more in their daily work.

Key Players

The “Global NGS Sample Preparation Market” study report will provide a valuable insight with an emphasis on the global market. The major players in the market are ILLUMINA, INC., Thermo Fisher Scientific Inc., PerkinElmer Inc., F. Hoffmann-La Roche Ltd, AGILENT TECHNOLOGIES, INC., Danaher, Becton, Dickinson and Company, Merck KGAA, QIAGEN, Bio-Rad Laboratories, PROMEGA CORPORATION, TECAN TRADING AG, Oxford Nanopore Technologies PLC, EUROFINS SCIENTIFIC, SWIFT BIOSCIENCES INC., SYSMEX CORPORATION, and Takara Bio Inc. 

Our market analysis also entails a section solely dedicated for such major players wherein our analysts provide an insight to the financial statements of all the major players, along with its product benchmarking and SWOT analysis. The competitive landscape section also includes key development strategies, market share and market ranking analysis of the above-mentioned players globally.

Key Developments

• Resolution Bioscience, a pioneer in the development and commercialization of NGS-based precision cancer treatments, was acquired by Agilent in 2021. Agilent’s NGS-based cancer detection capabilities were complemented and improved by Resolution Bioscience, which also gave Agilent access to cutting-edge technology to better meet the demands of the rapidly expanding precision medicine market.
• Roche said in 2020 that it has partnered with Illumina for a non-exclusive 15-year period in order to expand the use of distributable next-generation sequencing (NGS)-based tests in cancer.
• Thermo Fisher Scientific said in 2021 that it will purchase PPD, a provider of clinical research services.

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We'll dig into the market using both numbers and more human-focused aspects, breaking it down into segments based on economic stuff and things like consumer behavior. Then, we'll give you the market value in USD Billion for each of those segments and sub-segments. We'll also point out which region and segment we think will be the fastest-growing and which one will be king of the hill. You'll get a geographical analysis that shows where the product/service is really being used, plus the factors influencing the market in each area. Finally, we'll cover the competitive scene, including market rankings of the big players and any new service/product launches, partnerships, expansions, and acquisitions from the last five years. Expect detailed company profiles with overviews, insights, and product comparisons.