Global Lentiviral Vectors Market Size By Disease Indication, By Product Type, By Geographic Scope And Forecast
Published Date: August - 2024 | Publisher: MIR | No of Pages: 320 | Industry: latest updates trending Report | Format: Report available in PDF / Excel Format
View Details Buy Now 2890 Download Sample Ask for Discount Request CustomizationGlobal Lentiviral Vectors Market Size By Disease Indication, By Product Type, By Geographic Scope And Forecast
Lentiviral Vectors Market Size And Forecast
Lentiviral Vectors Market size was valued at USD 154.28 Million in 2024 and is projected to reach USD 360.19 Million by 2031, growing at a CAGR of 11.18% during the forecast period 2024-2031.
Global Lentiviral Vectors Market Drivers
The market drivers for the Lentiviral Vectors Market can be influenced by various factors. These may include
- Growing Need in Gene Therapy The capacity of lentiviral vectors to effectively transfer genetic information into target cells makes them a popular tool in gene therapy, which is causing demand to rise in this quickly developing sector.
- Growing Prevalence of Genetic Disorders As genetic disorders become more common, there is a greater need for efficient gene therapies, which drives up demand for lentiviral vectors as a means of delivering therapeutic genes.
- Biotechnology breakthroughs Continuous biotechnology breakthroughs, such as better vector design and manufacturing processes, are augmenting the safety and efficacy of lentiviral vectors, consequently broadening their applications and propelling market expansion.
- Increasing Use in Oncology The development of CAR-T cell treatments and cancer immunotherapies, among other oncology research and therapy applications, has led to a rise in the market for lentiviral vectors.
- A supportive regulatory environment is fostering the research and commercialization of lentiviral vector-based medicines and driving market expansion. This is due to favorable regulatory policies and the growing global acceptance of gene therapy by regulatory bodies.
- Growing Investments and financing Gene therapy technologies, such as lentiviral vectors, are the subject of significant public and private sector financing and investments, which are propelling innovation and commercialization efforts and expanding the market.
- Growth of the Biopharmaceutical Industry The development and commercialization of lentiviral vector-based therapies are being driven by the biopharmaceutical industry, which is expanding along with it. This is contributing to the growth of the market. Additionally, there is a growing partnership and collaboration between biotechnology companies and research institutions.
Global Lentiviral Vectors Market Restraints
Several factors can act as restraints or challenges for the Lentiviral Vectors Market. These may include
- Safety Issues and Regulatory Difficulties Notwithstanding developments, safety issues with lentiviral vectors for gene therapy, like the possibility of insertional mutagenesis and immunological reactions, provide regulatory difficulties and could impede market expansion.
- High Cost of Development and Production The high cost of lentiviral vector development, manufacturing, and quality control prevents them from being widely available and used, especially in areas with tight healthcare budgets. This, in turn, prevents the market from expanding.
- Complexity of Vector Design and Optimization The scalability and broad implementation of lentiviral vector-based therapies are impeded by the need for specialized knowledge and resources, which can be expensive and time-consuming. This is because lentiviral vector design and optimization are complex processes.
- Limited manufacturing Capacity and Scalability Problems with lentiviral vectors’ scalability and manufacturing capacity could prevent them from being produced in large enough quantities or affect their timely availability for clinical trials and commercialization, which would limit the market’s ability to grow.
- Competition from Alternative Vector Systems Alternative vector systems, like adeno-associated viruses (AAVs) and non-viral vectors, present lentiviral vectors with competitive challenges and may restrict market growth due to their advantages, such as lower immunogenicity and manufacturing costs.
- Ethical and Social Concerns Gene therapy-related ethical issues, such as those involving genetic engineering and the possibility of unexpected effects, could raise public doubt and regulatory attention, which would impede the uptake of lentiviral vector-based treatments and limit their market expansion.
- Intellectual Property Problems Licensing agreements and intellectual property conflicts pertaining to lentiviral vector technology have the potential to impede innovation and collaboration within the sector, impede new entrants, and ultimately limit market expansion.
Global Lentiviral Vectors Market Segmentation Analysis
The Global Lentiviral Vectors Market Segmented On the Disease Indication, Product Type, End-Users, And Geography
By Disease Indication
- β-thalassemia
- HIV
- Metachromatic Leukodystrophy
- X-linked Adrenoleukodystrophy
- Wiskott-Aldrich Syndrome
Based on Disease Indication, the market is segmented into β-thalassemia, HIV, Geography, Metachromatic Leukodystrophy, X-linked Adrenoleukodystrophy, And Wiskott-Aldrich Syndrome. β-thalassemia is a genetic blood disorder caused by mutations in the HBB gene that lead to reduced production of hemoglobin. Lentiviral vectors have been used to deliver a functional copy of the HBB gene to the patient’s hematopoietic stem cells, leading to increased production of hemoglobin and improvement in symptoms. Lentiviral vectors have been used to deliver gene editing tools such as CRISPR-Cas9 to target and remove the HIV virus from infected cells. The approach aims to cure HIV by eliminating the viral reservoirs in the body.
Metachromatic leukodystrophy is a rare genetic disorder caused by mutations in the ARSA gene that lead to the accumulation of toxic substances in the brain and nervous system. Lentiviral vectors have been used to deliver a functional copy of the ARSA gene to the patient’s brain cells, leading to reduced accumulation of toxic substances and improvement in symptoms.
By Product Type
- First Generation
- Second Generation
- Third Generation
Based on Product Type, the market is segmented into First Generation, Second Generation, and Third Generation. First Generation Lentiviral Vectors contain all the necessary genes for viral replication and packaging, but lack some of the genes required for efficient gene expression. As a result, they have relatively low transduction efficiency and are not commonly used for gene therapy. Second Generation Lentiviral Vectors are designed to overcome the limitations of first-generation vectors by incorporating additional genes that enhance gene expression and transduction efficiency. Third-Generation Lentiviral Vectorstors further improve upon the design of second-generation vectors by incorporating additional modifications to reduce immune response and improve safety.
By End-Users
- Hospitals
- Clinics
- Research Institutes
Based on End-Users, the market is segmented into Hospitals, Clinics, and Research Institutes. Lentiviral vectors can be used as a delivery system for gene therapy, where a functional copy of a defective gene is introduced into a patient’s cells to treat a genetic disorder. In a hospital or clinical setting, lentiviral vectors can be used to prepare and administer gene therapy to patients. Lentiviral vectors can also be used to modify a patient’s own T-cells to target cancer cells in a treatment called chimeric antigen receptor (CAR) T-cell therapy. In a hospital or clinical setting, lentiviral vectors can be used to prepare and administer CAR T-cell therapy to patients. Lentiviral vectors can be used as a research tool to study gene function and regulation, as well as to create animal models of human diseases. In a research institute, lentiviral vectors can be used to transduce cells or organisms in order to study gene function and disease mechanisms.
By Geography
- North America
- Europe
- Asia Pacific
- Latin America
- Middle East And Africa
On the basis of Geography, the Global Lentiviral Vectors Market is classified into North America, Europe, Asia Pacific, Latin America, the Middle East, and Africa. Due to the presence of significant market players and considerable technical improvement in the region, North America dominates the lentiviral vector market. Due to the rising frequency of cancers such as those of the bladder, oesophagus, liver, pancreas, and other organs, as well as the significant presence of large manufacturers, Asia-Pacific is predicted to expand at the fastest growth rate between 2023 and 2030. Advances in technology and an increase in foreign investment to provide growth opportunities.
Key Players
The major players in the Lentiviral Vectors Market are
- Cobra Biologics Limited
- Sirion-Biotech GmbH
- Merck KGaA
- FinVector Oy
- Oxford Biomedica
- OriGene Technologies Inc.
- Sino Biological Inc.
- Cell Biolabs
- Batavia Biosciences B.V.
- Lonza
- GENEMEDI
- Takara Bio Inc.
- Thermo Fisher Scientific Inc.
- Waisman Biomanufacturing
- Cytiva
- Thermo Fisher Scientific
- Sirion-Biotech GmbH (Revvity)
- Vector Biolabs
- OriGene Technologies, Inc.
- Takara Bio Inc.
- Merck KGaA
- Oxford Biomedica
Report Scope
| REPORT ATTRIBUTES | DETAILS |
|---|---|
| STUDY PERIOD | 2021-2031 |
| BASE YEAR | 2024 |
| FORECAST PERIOD | 2024-2031 |
| HISTORICAL PERIOD | 2021-2023 |
| UNIT | Value (USD Million) |
| KEY COMPANIES PROFILED | Cobra Biologics Limited, Sirion-Biotech GmbH, Merck KGaA, FinVector Oy, Oxford Biomedica, OriGene Technologies, Inc., Sino Biological Inc., Cell Biolabs, Inc. |
| SEGMENTS COVERED | By Disease Indication, By Product Type, By End-Users, And By Geography. |
| CUSTOMIZATION SCOPE | Free report customization (equivalent up to 4 analyst’s working days) with purchase. Addition or alteration to country, regional & segment scope. |
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