Global mRNA Therapeutics Market Size By Application (Rare Genetic Diseases, Oncology), By Type (Prophylactic Vaccines, Therapeutic Vaccines), By End-Use (Hospitals And Clinics, Research Organizations), By Geographic Scope And Forecast

mRNA Therapeutics Market Size And Forecast

mRNA Therapeutics Market size was valued at USD 31.04 Billion in 2022 and is projected to reach USD 35.82 Billion by 2030, growing at a CAGR of 1.8% from 2023 to 2030.

Increased prevalence of long-lasting and communicable diseases driving market expansion. Additionally, an increase in the number of patients with infectious diseases, cancer, influenza, and respiratory illnesses is expected to fuel market growth. The Global mRNA Therapeutics Market report provides a holistic evaluation of the market. The report offers a comprehensive analysis of key segments, trends, drivers, restraints, competitive landscape, and factors that are playing a substantial role in the market.

Global mRNA Therapeutics Market Definition

The basic principle of mRNA therapeutics involves the delivery of in vitro transcribed mRNA into a target cell, where the cellular machinery translates the mRNA into a functional protein. Whereas in therapeutic applications, an mRNA expressing an absent (or dysfunctional) protein in a patient delivers functional protein expression, in vaccine applications, an mRNA encoding a viral protein will elicit a protective immune response. As a result, the generation of vaccines, protein replacement therapy, and the treatment of genetic illnesses all make extensive use of mRNAs.

mRNA technology has a wide range of applications in the treatment or prevention of disease due to the essential function that mRNA plays in protein expression. Two mRNA-based coronavirus disease 2019 (COVID-19) vaccines have received Emergency Use Authorization, confirming the revolutionary method’s clinical viability. Lung and liver disorders are being treated with mRNA replacement therapy for hereditary diseases (inhaled and intravenous delivery). The inherent immunological adjuvant properties of mRNA can be used in immuno-oncologic strategies.

Global mRNA Therapeutics Market Overview

Increased Prevalence of Long-lasting and Communicable Diseases driving market expansion. Additionally, an increase in the number of patients with infectious diseases, cancer, influenza, and respiratory illnesses is expected to fuel market growth. For instance, an NCBI research said that in 2019, the WHO estimates that up to 500,000 people might die from influenza each year and that nearly one billion people will be unwell, which will likely lead to an increase in the number of hospitals and healthcare facilities.

Moreover, mRNA treatments, a rapidly increasing class of medications for numerous diseases, will revolutionize personalized medicine and alter current treatment protocols. It is anticipated that the mRNA-dependent product market will expand in the years to come. The rise in prevalence of rare diseases like propionic metabolic acidosis, sufficient concentration diabetic ketoacidosis, carbohydrate diseases, genetic defects, metabolic, and immunological disorders, as well as chronic diseases like heart disease, cancer, pulmonary, and CKD, is what is driving this market expansion. Because of its excellent potential for treating chronic diseases, RNA-based therapeutics have received a lot of interest in recent years.

So, it looks like pharmaceutical companies are really betting big on mRNA technology – it's a major growth driver because it lets them mix and match molecules to create new therapeutic drugs. But that's not all; we're also seeing significant investment in biotech R&D and awesome improvements in medical tech, all helping to push things forward. Plus, RNA vaccines? They're kind of a big deal because they're easier to make, distribute, and (importantly) safer than the older DNA vaccines. And because they've shown promise in human trials, the demand for mRNA vaccines and therapies is really taking off. Think about the success of the COVID-19 vaccines from Moderna and Pfizer-BioNTech – that's fueled a huge jump in mRNA-based vaccine treatments being tested, especially in oncology clinical trials.

Global mRNA Therapeutics MarketSegmentation Analysis

The Global mRNA Therapeutics Market is Segmented on the basis of Application, Type, End-Use, and Geography.

mRNA Therapeutics Market, By Application

• Rare Genetic Diseases
• Oncology
• Respiratory Diseases
• Infectious Diseases
• Others

When we look at Application, the market is broken down into areas like Rare Genetic Diseases, Oncology, Respiratory Diseases, Infectious Diseases, and, well, just Others. Back in 2021, Infectious Diseases was where most of the money was being made. What's driving all this? Think about itmRNA-based vaccines are becoming more popular, lots of new drugs are entering clinical trials to fight various infectious diseases, and of course, there's the whole COVID-19 thing that started in 2019. Looking ahead, we're expecting the oncology segment to really take off. After all, the WHO estimates that cancer caused around 10 million deaths in 2020, making it a leading killer worldwide.

mRNA Therapeutics Market, By Type

• Prophylactic Vaccines
• Therapeutic Vaccines
• Therapeutic Drugs

Based on Type, the market is segmented into Prophylactic Vaccines, Therapeutic Vaccines, and Therapeutic Drugs. The prophylactic vaccines segment dominated the market in 2021 with a significant market share. Prophylactic vaccinations are the focus of current R&D efforts, according to the article in Nature, with 77% of mRNA businesses having at least one preventive vaccine under development. Other vaccines for disorders including influenza and respiratory syncytial virus also contribute to the category growth, but COVID-19 products currently account for the vast bulk of preventive vaccine revenues.

mRNA Therapeutics Market, By End-Use

• Hospitals & Clinics
• Research Organizations
• Others

Based on End-Use, the market is segmented into Hospitals & Clinics, Research Organizations, and Others. In 2021, the hospitals and clinics segment had the largest revenue share, and it is anticipated that it will grow at the fastest rate over the next few years. The market for personalized pharmaceuticals is expanding as a result of the increased use of treatments and vaccines to treat a variety of chronic conditions. The increasing number of patients visiting hospitals and clinics is another factor driving this market segment.

mRNA Therapeutics Market, By Geography

• North America
• Europe
• Asia Pacific
• Latin America
• Middle East & Africa

When we look at where mRNA therapeutics are being used around the world, we can break it down by regionNorth America, Europe, Asia Pacific, Latin America, and the Middle East & Africa. Right now, North America is leading the way, holding a big chunk of the market in 2021, and it's expected to grow the quickest over the next few years. Why? Well, there's a lot of research money flowing in, more government programs are focusing on RNA-based treatments, and there are tons of clinical trials happening. Think about iteven back in November 2020, researchers like Graham were getting support from the National Institutes of Health (NIH), the Defense Department, and academic labs that are federally financed. That support was a major reason we were able to develop COVID-19 vaccines so quickly. And speaking of vaccines, the government has pumped an extra $10.5 billion into vaccine companies since the pandemic started, all to get those vaccines out to people faster.

Key Players

The “Global mRNA Therapeutics Market” study report will provide valuable insight with an emphasis on the global market. The major players in the market are Moderna, Inc., BioNTech SE, CureVac N.V., Arcturus Therapeutics, Translate Bio, Inc., GSK plc., Argos Therapeutics Inc., Sangamo Therapeutics, Inc., Pfizer Inc., AstraZeneca plc., and CRISPR Therapeutics AG. The competitive landscape section also includes key development strategies, market share, and market ranking analysis of the above-mentioned players globally.

Ace Matrix Analysis

The Ace Matrix provided in the report would help to understand how the major key players involved in this industry are performing as we provide a ranking for these companies based on various factors such as service features & innovations, scalability, innovation of services, industry coverage, industry reach, and growth roadmap. Based on these factors, we rank the companies into four categories as Active, Cutting Edge, Emerging, and Innovators.

Market Attractiveness

The image of market attractiveness provided would further help to get information about the region that is majorly leading in the Global mRNA Therapeutics Market. We cover the major impacting factors that are responsible for driving the industry growth in the given region.

Porter’s Five Forces

The image provided would further help to get information about Porter’s five forces framework providing a blueprint for understanding the behavior of competitors and a player’s strategic positioning in the respective industry. Porter’s five forces model can be used to assess the competitive landscape in the Global mRNA Therapeutics Market, gauge the attractiveness of a certain sector, and assess investment possibilities.

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Reasons to Purchase this Report

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