Global Bispecific Antibody Market Size By Drug Type (Blinatumomab, Catumaxomab), By Indication (Cancer, Infectious Disease), By Distribution Channel (Hospital Pharmacies, Retail Pharmacies), By Geographic Scope And Forecast

Bispecific Antibody Market Size And Forecast

Bispecific Antibody Market size is growing at a faster pace with substantial growth rates over the last few years and is estimated that the market will grow significantly in the forecasted period i.e., 2022 to 2030.

The rise in special designation from regulatory authorities is projected to be a major factor driving the growth of the bispecific antibody market during the forecast period. Furthermore, the continuous clinical trials done by various pharmaceutical industries are expected to drive the expansion of the bispecific antibody market. The Global Bispecific Antibody Market report provides a holistic evaluation of the market. The report offers a comprehensive analysis of key segments, trends, drivers, restraints, competitive landscape, and factors that are playing a substantial role in the market.

Global Bispecific Antibody Market Definition

A bispecific antibody (BsAb) is an artificial protein made up of fragments of two distinct monoclonal antibodies that can bind to two different types of antigens. Quadromas, chemical heteroconjugates, bispecific antibodies with particular heterodimerization domains, and bispecific antibodies of minimum size are all examples of bispecific antibody forms. Bispecific antibodies are largely used in cancer therapy and are developing as a revolutionary technique for two targeting methods inside a single molecule for cancer treatment.

Bispecific antibodies enhance and assure the following properties in a cancer-targeted agentincreased binding capacity, selectivity, and effectiveness. It has been discovered that bispecific antibodies had superior efficacy for cancer treatment when compared to combination therapy with the other two antibodies. The backbone of the fast growth of bispecific antibody formats has been recognized as recombinant DNA technology.

Bispecific antibodies? They're turning into the real rockstars of cancer treatment these days, showing promise against tough foes like breast, lung, prostate, and colon cancer. And with cancer cases on the rise – you know, things like lung, breast, and even cervical cancer becoming more common – the market for these therapies is really taking off. Plus, get thisthe California Journal of Clinical Cancer (CJCC) says about one in six guys in the U.S. has had a prostate cancer screening at some point. That's a lot! But, it's not all smooth sailing. This bispecific antibody treatment stuff? It's pretty complicated, especially when it comes to figuring out if it's working (detection). That complexity might just slow down how quickly it catches on around the world over the next few years.

Global Bispecific Antibody Market Overview

The bispecific antibody market is really taking off, and a big part of that is because we desperately need better treatments for tough things like infectious diseases, nasty cancer tumors, and even bacterial infections. We're seeing more and more people diagnosed with cancer and infectious illnesses, which means we've got to find cures! Think about itresearchers have found that some bispecific antibody cytokines are super important in how inflammatory and autoimmune diseases develop, as noted in the Journal of Hematology & Oncology. So, blocking these cytokines could be a way to treat inflammatory and infectious problems. We already know that TNF-inhibition works for things like psoriasis, psoriatic arthritis, Crohn’s disease, ulcerative colitis, and a bunch of other conditions. And here's a scary statthe WHO says infectious diseases cause 9.5 million deaths every year, which hits society hard financially. That's why healthcare systems around the world are using surveillance to catch infectious illnesses early and stop them from spreading. Plus, in 2018 alone, a staggering 18.1 million people were diagnosed with cancer worldwide, and sadly, 9.6 million lost their battle.

And get this – the rise in Covid-19 cases is actually fueling market growth! One cool way to fight Covid is with bispecific antibodies, which can boost antibody power. You know, according to the Taylor and Francis mAbs Journal, tons of SARS-CoV-2 neutralizing bispecific antibodies have been found. Most of them work by stopping the virus's Spike receptor-binding domain (RBD) from hooking up with angiotensin-converting enzyme (ACE2). Now, there are these things called Fabs – they're antigen-binding fragments from phage display that stick to RBD, but they don't block ACE2 or kill the virus. But here's the kickerwhen they combined these non-neutralizing Fabs into a bispecific VH/Fab immunoglobulin with a neutralizing VH domain, it was amazing! Compared to using the mono-specific bivalent VH-Fc alone or a cocktail of VH-Fc and Immunoglobulin, they saw a 25-fold jump in neutralizing SARS-CoV-2. So, building a bispecific antibody that targets both neutralizing and non-neutralizing spots on Spike-RBD? It's a pretty smart and effective way to make SARS-CoV-2 antibodies work even better.

However, the high cost of pharmaceuticals and R&D expenditure may limit the worldwide bispecific antibody market’s growth. Despite this, increased research and development initiatives in this industry may generate new prospects for the market’s future growth.

Global Bispecific Antibody MarketSegmentation Analysis

The Global Bispecific Antibody Market is segmented based on Drug Type, Indication, Distribution Channel, and Geography.

Bispecific Antibody Market, By Drug Type

• Blinatumomab• Catumaxomab• Duligotumab

Based on Drug Type, the market is further segmented into Blinatumomab, Catumaxomab, and Duligotumab. The medicine type blinatumomab generates the most revenue in the bispecific antibody market. Blinatumomab is used to treat specific kinds of acute lymphocytic leukemia in adults and children that have not improved or have returned despite therapy with other drugs.

Bispecific Antibody Market, By Indication

• Cancer• Infectious Disease• Inflammatory and Autoimmune Disorders• CNS Disorders

Based on Indication, the market is segmented into Cancer, Infectious Disease, Inflammatory and Autoimmune Disorders, CNS Disorders. Cancer is expected to be the greatest revenue-generating segment because of its enormous patient population. Cancer immunotherapy is the most extensively researched use of bispecific antibodies. BsAb has a broader range of uses, including lung, breast, and colon cancer. A bispecific antibody attaches to a cytotoxic cell and a tumor cell at the same time and eliminates both. Bispecific antibodies, a technologically sophisticated solution for two targeting techniques inside the same molecule, are emerging.

Bispecific Antibody Market, By Distribution Channel

• Hospital Pharmacies• Retail Pharmacies• Drug stores• Online Pharmacies

Based on Distribution Channel, the market is segmented into Hospital Pharmacies, Retail Pharmacies, Drug Stores, Online Pharmacies. Hospital pharmacies segment is dominating the market followed by retail pharmacies. Online pharmacies, on the other hand, are likely to rise at a rapid pace over the forecast period due to improvements in digital technologies in the bispecific antibody market.

Bispecific Antibody Market, By Geography

• North America• Europe• Asia Pacific• Rest of the World

When we look at different regions, the global bispecific antibody market breaks down into North America, Europe, Asia Pacific, and the Rest of the World. Turns out, North America and Europe have the biggest bispecific antibodies treatment market because a lot of the big players are located there. Plus, they see the highest number of new cancer cases each year – things like lung, prostate, breast, and cervical cancer. Also, those favorable government initiatives? They're really helping the market for this therapy grow in North America and Europe. On the other hand, Asia-Pacific is still a bit behind in bispecific antibody therapy because some countries there just don't have the best healthcare. But! With a bunch of investment going into healthcare infrastructure (think healthcare cost, healthcare facility, and healthcare budget), there's a ton of potential for the Asian market to really take off.

Key Players

The “Global Bispecific Antibody Market” study report will provide valuable insight with an emphasis on the global market. The major players in the market are Merck, Amgen, Johnson & Johnson, AbbVie Inc., Bayer AG, Pfizer Inc., Bristol-Myers Squibb, Sonafi S.A., OncoMed Pharmaceuticals, Portola Pharmaceuticals, Ganymed Pharmaceuticals amongst others are a few major companies operating in the Bispecific Antibody Market. The competitive landscape section also includes key development strategies, market share, and market ranking analysis of the above-mentioned players globally.

Key Developments

• In January 2019, the Chinese Academy of Medical Sciences and Peking Union Medical College collaborated to create a novel bispecific aptamer that boosts immune cytotoxicity against MUC1-positive tumor cells.

• In September 2018, researchers from China Pharmaceutical University created and generated a completely human, bispecific, single-chain diabody that can bind to VEGF165 and programmed death-1 in Pichia pastoris.

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