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Global HLA Typing For Transplant Market Size By Product And Service (Reagents And Consumables, Instruments, Software And Services), By Technology (Molecular Assay, Non-Molecular Assay), By Transplant Type (Solid Organ, Soft Tissue), By Application (Diagnostic Applications, Research Applications), By


Published on: 2024-08-04 | No of Pages : 320 | Industry : latest updates trending Report

Publisher : MIR | Format : PDF&Excel

Global HLA Typing For Transplant Market Size By Product And Service (Reagents And Consumables, Instruments, Software And Services), By Technology (Molecular Assay, Non-Molecular Assay), By Transplant Type (Solid Organ, Soft Tissue), By Application (Diagnostic Applications, Research Applications), By

HLA Typing For Transplant Market Size And Forecast

HLA Typing For Transplant Market size was valued at USD 845.7 Million in 2023 and is projected to reach USD 1,555.5 Million by 2031, growing at a CAGR of 7.92% from 2024 to 2031.

  • HLA typing, or Human Leukocyte Antigen typing, is the process of matching patients and donors for organ, tissue, or bone marrow transplants.
  • It entails detecting and comparing the major histocompatibility complex (MHC) proteins on cell surfaces, which play an important role in the immune system’s detection of foreign compounds.
  • The use of HLA typing in transplantation is critical to improving the success rates of these procedures. It is used in kidney, liver, heart, lung, and bone marrow transplants to verify that the donor organ or cells are as compatible as possible with the recipient, reducing the risk of transplant rejection.
  • Additionally, HLA typing is utilized in disease association studies to determine whether certain HLA types are associated with an increased or decreased risk of various diseases, which helps us understand autoimmune diseases, infectious diseases, and pharmacogenomics.

Global HLA Typing For Transplant Market Dynamics

The key market dynamics that are shaping the HLA Typing For Transplant Market include

Key Market Drivers

  • Rising Demand for Organ TransplantsThe global increase in organ failure cases caused by chronic diseases such as diabetes and heart failure is spurring up the demand for organ transplantation. Thus, HLA typing is essential for matching donors and recipients, fueling the demand for precise and efficient typing technology.
  • Advancements in HLA Typing TechnologyMolecular assay techniques such as Next-Generation Sequencing (NGS) and Polymerase Chain Reaction (PCR) have improved accuracy and speed in HLA typing. These enhancements improve matching accuracy, minimize transplant wait times, and drive the use of these technologies.
  • Increased Awareness and Government Initiatives Growing public awareness of organ donation, as well as government attempts to encourage it, is bolstering the number of donors. As a result, HLA typing services are increasingly required to verify transplant compatibility and success rates.
  • Expansion of Transplantation ApplicationsHLA typing is increasingly being used in stem cell transplantation, tissue transplantation, and personalized medicine, in addition to traditional organ transplants. This expanded breadth emphasizes the necessity of HLA typing in numerous medical procedures, propelling market growth and innovation.

Key Challenges

  • High Costs of Advanced HLA Typing Technologies Adoption of cutting-edge technology such as Next-Generation Sequencing (NGS) for HLA typing incurs large expenses, making it less accessible in developing nations. These costs include not just the equipment but also maintenance, reagents, and qualified personnel, creating a barrier to widespread market adoption.
  • Complexity of the HLA System The human leukocyte antigen (HLA) system for transplantation is extremely complex, with a large number of alleles to identify for proper typing. This complexity makes it difficult to establish generally effective typing systems, which could impair donor-recipient matching accuracy and hinder market expansion.
  • Shortage of Skilled ProfessionalsThere is a significant scarcity of healthcare personnel educated in sophisticated HLA typing for transplant techniques, which limits transplant centers’ ability to execute these tests effectively. This shortage slows down the transplant procedure and has an impact on patient outcomes, limiting market expansion.

Key Trends

  • Increasing Adoption of Next-Generation Sequencing (NGS) Due to its high resolution and capacity to detect uncommon alleles, which improves matching accuracy between donors and recipients, NGS is quickly emerging as the industry standard for HLA typing in transplants. This trend indicates a shift towards more precise and efficient transplant matching procedures.
  • Rise of Point-of-Care HLA Typing The introduction of portable, quick HLA typing kits for transplants enables point-of-care testing, shortening the period between typing and transplantation. This improvement is critical in emergency settings, increasing the likelihood of transplant success and patient survival rates.
  • Expansion of HLA Typing in Regenerative Medicine HLA typing in transplants is becoming more common in regenerative medicine, particularly stem cell therapy and tissue engineering. This trend emphasizes the need for exact HLA matching in increasing the success rates of novel treatments and widening the applications of HLA typing.

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Global HLA Typing For Transplant Market Regional Analysis

Here is a more detailed regional analysis of the HLA Typing For Transplant Market

North America

  • According to Market Research, North America is estimated to dominate during the forecast period. North America, particularly the United States, has a modern healthcare infrastructure, with major investments in research and development. This environment promotes the use of cutting-edge HLA typing for transplant technology, resulting in market domination through efficient and accurate transplant matching processes.
  • Chronic diseases are prevalent in the region, including diabetes and heart disease, resulting in an increased demand for organ donations. This demand raises the requirement for precise HLA typing to ensure effective transplant results, which strengthens the market in North America.
  • The presence of favourable regulatory rules and substantial financing for organ transplantation and genetic research in North America promotes breakthroughs in HLA typing for transplant technology. Important roles include federal funding for transplantation research and initiatives by institutions such as the NIH.
  • Furthermore, in North America, there is widespread awareness of the importance of organ donation, which is backed by effective organ donation programs and campaigns. This increased awareness leads to a greater number of organ donors, which increases the demand for HLA typing for transplant services to appropriately match donors and recipients.

Asia Pacific

  • Asia Pacific is estimated to grow at the highest CAGR during the forecast period. Asia Pacific countries are experiencing tremendous expansion in healthcare infrastructure and investments, allowing for the adoption of new medical technology such as HLA testing for transplants. This expansion is critical to meeting the region’s growing need for organ transplantation and tissue-matching services.
  • The region’s rising burden of chronic diseases, such as diabetes, cardiovascular disease, and renal problems, is driving up demand for organ transplants. This tendency demands enhanced HLA typing for transplant treatments to assure successful outcomes, hence boosting market expansion.
  • Furthermore, the value of organ donation is becoming more widely recognized in Asia Pacific, due to government measures targeted at boosting the number of organ donors. These activities are critical for increasing demand for HLA typing for transplant services, which ensures compatibility and success in transplants.

Europe

  • Europe has robust healthcare systems, with significant government and private funds allocated to transplantation and research. This financial support encourages the use of enhanced HLA typing for transplant technologies and procedures, fueling market growth by improving the efficiency and effectiveness of transplant matching processes.
  • European countries frequently have high rates of organ donation, which is aided by favorable organ donation regulations and public awareness efforts. As the supply of organs for transplantation increases, so does the demand for HLA typing for transplant services to precisely and quickly match organs to recipients.
  • Furthermore, there are various collaborative research projects and consortiums in Europe aimed at improving transplantation outcomes and immunogenetics. These agreements promote innovation in HLA typing for transplant procedures and protocols, which benefits the region’s market growth by increasing transplant success rates.

Global HLA Typing For Transplant MarketSegmentation Analysis

The Global HLA Typing For Transplant Market is segmented on the basis of Product & Service, Technology, Transplant Type, Application, End-User, And Geography.

HLA Typing For Transplant Market, By Product & Service

  • Reagents & Consumables
  • Instruments
  • Software & Services

Based on Product & Service, The market is segmented into Reagents & Consumables, Instruments, and Software & Services. The reagent and consumable segment is estimated to dominate the HLA Typing For Transplant Market due to the repeated use of these items in the HLA typing transplant process. Unlike instruments, which are capital investments made periodically, reagents and consumables are utilized in every HLA typing for the transplant procedure, necessitating frequent repurchases. Their critical role in maintaining the quality and reproducibility of HLA typing results, combined with the increasing amount of transplant procedures worldwide, generates ongoing demand.

HLA Typing For Transplant Market, By Technology

  • Molecular Assay Technologies
    1. PCR-based Molecular Assays
    2. Sequencing-based Molecular Assays
  • Non-molecular Assay Technologies

Based on Technology, The market is segmented into Molecular Assay Technologies and Non-molecular Assay Technologies. The molecular assay technology segment is estimated to exhibit the highest growth in the market over the forecast period due to the better precision and accuracy that sequencing-based approaches, such as Next-Generation Sequencing (NGS) provide. NGS offers a complete investigation of the HLA gene’s complexity and multiple variations, resulting in very accurate donor-recipient matching for transplants. This accuracy is critical for lowering the risk of transplant rejection and enhancing patient outcomes.

HLA Typing For Transplant Market, By Transplant Type

  • Solid Organ Transplant
  • Soft Tissue Transplant

Based on Transplant Type, The market is segmented into Solid Organ Transplant and Soft Tissue Transplant. The solid organ transplant segment is estimated to lead this segment in the forecast period owing to the larger occurrence of organ failure cases, which has resulted in a greater demand for organ transplants such as kidneys, livers, hearts, and lungs. Solid organ transplants are crucial life-saving procedures for patients with end-stage organ failure, and they necessitate precise HLA typing in transplant to ensure donor-recipient compatibility and reduce the risk of transplant rejection.

HLA Typing For Transplant Market, By Application

  • Diagnostic Applications
    1. Antibody Screening
    2. Chimerism Monitoring
    3. Others
  • Research Applications

Based on Application, The market is segmented into Diagnostic Applications and Research Applications. The diagnostic application segment is estimated to hold the majority share in the HLA Typing For Transplant Market during the forecast period due to the essential role diagnostic apps play in the pre-and post-transplantation processes. Diagnostic applications such as antibody screening and chimerism monitoring are critical for finding prospective donors, confirming compatibility, and monitoring post-transplant immunological responses to avoid graft rejection. Antibody screening is critical for determining the recipient’s susceptibility to potential donor antigens, lowering the likelihood of transplant rejection.

HLA Typing For Transplant Market, By End-User

  • Independent Reference Laboratories
  • Hospitals & Transplant Centers
  • Research Laboratories & Academic Institutes

Based on End-User, The market is segmented into Independent Reference Laboratories, Hospitals & Transplant Centers, and Research Laboratories & Academic Institutes. The hospitals & transplant centers segment is estimated to show the highest growth in the forecasted period due to these facilities’ direct involvement in organ procurement and transplantation. Hospitals and transplant centers are at the forefront of patient care, offering immediate and comprehensive treatments such as organ transplant procedures, pre-transplant evaluations, and post-transplant follow-up.

Key Players

The “Global HLA Typing For Transplant Market” study report will provide valuable insight with an emphasis on the global market. The major players in the market are Abbott Laboratories, Thermo Fisher Scientific, F. Hoffmann-La Roche Ltd, Illumina, QIAGEN, PerkinElmer Inc., CareDx, InVitae Corporation, Omixon Ltd, GenDx, Allogene Therapeutics, City of Hope, Korean Red Cross Blood Center, and exacOmics GmbH.

Our market analysis also entails a section solely dedicated to such major players wherein our analysts provide an insight into the financial statements of all the major players, along with its product benchmarking and SWOT analysis. The competitive landscape section also includes key development strategies, market share, and market ranking analysis of the above-mentioned players globally.

HLA Typing For Transplant Market Recent Developments

  • In November 2022, Illumina, Inc. launched a new Solutions Centre in Dubai to focus on increasing genomics research in the Middle East. This shows an emphasis on expanding the application of HLA typing technology.
  • In March 2022, Immucor, Inc. released MIA FORA NGS Express HLA Typing Software. This software streamlines the procedure, which could make HLA typing faster and more efficient.

Report Scope

Report AttributesDetails
Study Period

2020-2031

Base Year

2023

Forecast Period

2024-2031

Historical Period

2020-2022

Unit

Value (USD Million)

Key Companies Profiled

Abbott Laboratories, Thermo Fisher Scientific, F. Hoffmann-La Roche Ltd, Illumina, QIAGEN, PerkinElmer Inc., CareDx, InVitae Corporation, Omixon Ltd.

Segments Covered

By Product & Service, By Technology, By Transplant Type, By Application, By End-User, And By Geography.

Customization scope

Free report customization (equivalent to up to 4 analyst working days) with purchase. Addition or alteration to country, regional & segment scope.

Research Methodology of Market Research

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Reasons to Purchase this Report

• Qualitative and quantitative analysis of the market based on segmentation involving both economic as well as non-economic factors• Provision of market value (USD Billion) data for each segment and sub-segment• Indicates the region and segment that is expected to witness the fastest growth as well as to dominate the market• Analysis by geography highlighting the consumption of the product/service in the region as well as indicating the factors that are affecting the market within each region• Competitive landscape which incorporates the market ranking of the major players, along with new service/product launches, partnerships, business expansions and acquisitions in the past five years of companies profiled• Extensive company profiles comprising of company overview, company insights, product benchmarking and SWOT analysis for the major market players• The current as well as a future market outlook of the industry with respect to recent developments (which involve growth opportunities and drivers as well as challenges and restraints of both emerging as well as developed regions• Includes in-depth analysis of the market of various perspectives through Porter’s five forces analysis• Provides insight into the market through Value Chain• Market dynamics scenario, along with growth opportunities of the market in the years to come• 6-month post-sales analyst support

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