Global Oral Proteins And Peptides Market Size By Drug Type (Linaclotide, Insulin, Plecanatide, Calcitonin, Octreotide), By Application (Bone Disease, Neurological Disorders, Diabetes, Metabolic Disorders, Hormonal Disorder), By Geographic Scope And Forecast

Oral Proteins And Peptides Market Size And Forecast

Oral Proteins And Peptides Market size was valued at USD 1.3 Billion in 2024 and is projected to reach USD 8.1 Billion by 2031, growing at a CAGR of 19% during the forecast period 2024-2031.

The need for oral peptide and protein-based treatments has expanded dramatically as the prevalence of chronic diseases has increased, patient preference for oral medications has increased, and patient compliance has improved. More, an increase in the geriatric population, as well as improvements in healthcare settings, drive the market. Nevertheless, high costs incurred with oral peptides and proteins, as well as reduced absorption of these medications in the body, limit market expansion.

Furthermore, increased R&D by pharmaceutical corporations and an increase in the disposable income of emerging economies present profitable opportunities to market participants. There were 21 peptide drugs in development for the treatment of COVID-19 as of May 2020, including 15 synthetic peptides for the diagnosis of acute respiratory distress syndrome and other respiratory ailments caused by SARS-Cov-2 infection. As a result, peptide medications are being evaluated as a therapy option for COVID-19, COVID-19 may have a beneficial effect on the peptide therapeutics industry.

Global Oral Proteins And Peptides Market Definition

A recommended treatment for allergic reactions to things such as grass pollens, home dust mites, or bee venom, allergy immunotherapy identifies the origin of the allergy in order to provide instant and long-lasting alleviation in the allergic reaction. Injection of the allergen, which causes allergy symptoms, is used as part of the treatment. In order to identify allergens, a medical examination conducted by a skilled allergist or immunologist, as well as allergy skin or allergy blood tests, must be performed in conjunction. It is also referred to as allergy injections when it comes to allergy immunotherapy.

Allergy injections can be administered to both children and adults; however, they are not especially suggested for children under the age of five. Allergy injections lessen irritability to allergens and, in many cases, result in long-term alleviation of allergy symptoms, even after the therapy has been discontinued. This makes it a more cost-effective and useful treatment technique for a larger number of patients. In many cases, allergy injections have been demonstrated to help alleviate the symptoms of allergies. It has the potential to prevent the formation of new allergens, as well as the progression of allergic illnesses in children, ranging from allergic rhinitis to asthma.

The success of allergy injections appears to be connected to the length of the treatment programs as well as the amount of the allergen that is being administered. Ideally, this form of therapy should be administered by a qualified physician in a facility that is equipped with highly-trained staff as well as technologies that can detect and manage adverse responses to allergy injections. In an ideal world, immunotherapy would be administered in the office of an allergist or immunologist. If this is not feasible, an immunologist should provide the supervising physician with full information on the use of allergy shot treatments in the first instance.

Global Oral Proteins And Peptides Market Overview

The rising number of patients suffering from chronic diseases, the increasing incidence of the geriatric population around the world, consumer preferences for oral drugs, rising demand for effective treatments and technology, increased joint work between pharmaceutical companies, and rising amount of investment for the development of healthcare facilities are some of the major and vital factors that will likely augment the growth of the Oral Proteins And Peptides Market.

On the other hand, rising consumer spending power, as well as an increase in the number of R&D activities by pharmaceutical companies, would contribute to the expansion of the Oral Proteins And Peptides Market over the forecast period. However, present uses of peptide therapies in oncology, metabolic disorders, and other fields have been hampered by drug shortages and supply chain concerns, as well as the delayed development of clinical trials involving non-COVID-19 medicines.

The high costs associated with therapeutic development, as well as the product’s limited availability, would most likely operate as market restrictions for the expansion of oral peptides and proteins in the above-mentioned timeframe. The unawareness among individuals in emerging economies will be the most significant and immediate impediment to the market’s growth. Furthermore, the poor absorption of oral proteins and peptides restricts their usage. Nonetheless, continuous advancement and expanding R&D activities are likely to overcome the aforementioned limitations and create profitable growth for the Oral Proteins And Peptides Market in the future years.

Global Oral Proteins And Peptides MarketSegmentation Analysis

The Global Oral Proteins And Peptides Market is Segmented on the basis of Drug Type, Application, and Geography.

Oral Proteins And Peptides Market, By Drug Type

• Linaclotide• Calcitonin• Insulin• Plecanatide• Octreotide

Based on Drug Type, the market is segmented into Linaclotide, Insulin, Plecanatide, Calcitonin, and Octreotide. Linaclotide is used to manage IBS with constipation in adults. Plecanatide is an FDA-approved medication used to treat chronic idiopathic constipation and IBS with constipation. Calcitonin, also known as thyrocalcitonin, is a protein hormone that is generated and secreted largely by parafollicular cells in the thyroid gland in humans and other mammals. Insulin is a protein that belongs to a class of proteins known called insulin analogs, which can be used for medical purposes such as the treatment of diabetes mellitus type II, also known as noninsulin-dependent diabetes mellitus or adult-onset diabetes mellitus (NIDDM).

Octreotide is a somatostatin analog that suppresses secretion and motility functions controlled by growth hormone, glucagon, vasoactive intestinal peptide, motilin, and other hormones. Thus, it suppresses a variety of endocrine activities, including gastrin release from G-cells, which reduces acid generation; delaying GI activity, which leads to stool creation with a shorter transit time via inhibition of gastrointestinal hormones. It has been marketed by brand names like Sandostatin LAR Depot, among others.

Oral Proteins And Peptides Market, By Application

• Gastrointestinal Disorders• Bone Disease• Neurological Disorders• Diabetes• Metabolic Disorders• Hormonal Disorder• Cancer

Based on Application, the market is segmented into Gastrointestinal Disorders, Bone Disease, Neurological Disorders, Diabetes, Metabolic Disorders, Hormonal Disorder, and Cancer. Because of their high specificity, selectivity, tiny sizes, simplicity of alteration, and high biocompatibility, peptides offer promising prospects in cancer-targeted medication delivery. The increasing prevalence of cancer worldwide, as well as the rising prescription of peptide therapies for cancer therapy, are the primary factors driving this segment’s domination. As per the International Agency for Research on Cancer- GLOBOCAN 2020 estimate, there will be 19,292,789 new cancer cases diagnosed globally in 2020, with 9,958,133 cancer deaths.

Furthermore, the five-year prevalence of cancer was expected to be 50,550,287 worldwide. The global incidence of new cases of cancer is anticipated to achieve 28,887,940 by 2040. As a result, the increasing prevalence of cancer cases worldwide is predicted to play a significant influence in the expansion of the analyzed segment during the forecast period. Furthermore, increasing awareness among patients and healthcare professionals about the negative consequences of chemotherapy and/or radiation therapy is a crucial reason driving the increased emphasis on alternative medicines such as peptide-based drugs.

Oral Proteins And Peptides Market, By Geography

• North America• Europe• Asia Pacific• Rest of the world

On the basis of Regional Analysis, the Global Oral Proteins And Peptides Market is segmented into North America, Asia-Pacific, Europe, and the Rest of the world. North America region’s market share is expanding due to factors such as rising awareness of peptide therapeutic products, the growing need for diagnostics in cancer and other disorders, and the expanding biotechnology industry.

Increased R&D spending by governments and significant players is also predicted to assist peptide therapies to maintain their supremacy in the next years. In this region, a well-established pharmaceutical and biopharmaceutical industry is a primary driver of growth. Due to expanding population and massive government and private sector investment in research and development, the Asia-Pacific region is predicted to grow at the fastest CAGR throughout the forecasted period. Furthermore, the region’s fast-increasing biopharmaceutical industry is propelling the growth of the oral peptides and proteins market.

Key Players

The “Global Oral Proteins And Peptides Market” study report will provide valuable insight with an emphasis on the global market. The major players in the market are Allergan, Merck & Co. Inc, Pfizer, Inc., Novo Nordisk, Hoffmann-La Roche, Sanofi, AstraZeneca, Bristol-Myers Squibb Company, Tarsa Therapeutics Inc, Biocon, Generex Biotechnology, Synergy Pharmaceuticals, Synthetic Biologics, Hovione, Novartis.

Our market analysis also entails a section solely dedicated to such major players wherein our analysts provide an insight into the financial statements of all the major players, along with its product benchmarking and SWOT analysis. The competitive landscape section also includes key development strategies, market share, and market ranking analysis of the above-mentioned players globally.

Key Developments

• February 2022 – Novo Nordisk announced the release of oral semaglutide in India, calling the drug the world’s first “peptide in a pill” for blood sugar control. Semaglutide is a GLP-1 receptor analog, a type of diabetes drug that is available in an injectable form, which is appealing to people who are afraid of needles.

• September 2021 – Nimble Therapeutics and Incyte have entered into a strategic research agreement to discover further innovative peptide treatments.

• May 2021 – ISSAR Pharmaceuticals made the decision to license out its peptide-based novel chemical entities or NCEs with pre-IND filing and a US Patents for various unmet healthcare requirements of the people, making it inexpensive and accessible for improved health results.

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• Qualitative and quantitative analysis of the market based on segmentation involving both economic as well as non-economic factors• Provision of market value (USD Billion) data for each segment and sub-segment• Indicates the region and segment that is expected to witness the fastest growth as well as to dominate the market• Analysis by geography highlighting the consumption of the product/service in the region as well as indicating the factors that are affecting the market within each region• Competitive landscape which incorporates the market ranking of the major players, along with new service/product launches, partnerships, business expansions, and acquisitions in the past five years of companies profiled• Extensive company profiles comprising of company overview, company insights, product benchmarking, and SWOT analysis for the major market players• The current as well as the future market outlook of the industry with respect to recent developments which involve growth opportunities and drivers as well as challenges and restraints of both emerging as well as developed regions• Includes in-depth analysis of the market of various perspectives through Porter’s five forces analysis• Provides insight into the market through Value Chain• Market dynamics scenario, along with growth opportunities of the market in the years to come• 6-month post-sales analyst support

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