Global Protein Stability Analysis Market Size By Product (Reagents and Assay Kits, Instruments, Consumables and Accessories, and Software), By Technique (Chromatography, Spectroscopy, and Surface Plasmon Resonance), By End User (Pharmaceutical and Biotechnological Companies, Contract Research Organi

Protein Stability Analysis Market Size And Forecast

Protein Stability Analysis Market size was valued at USD 7.5 Billion in 2024 and is projected to reach USD 16.4 Billion by 2031, growing at a CAGR of 11.35% from 2024 to 2031.

Protein stability analysis is one of the basic assays that are performed in research laboratories and pharmaceutical companies and therefore the Protein Stability Analysis Market is on a rise. Pharmaceutical companies are constantly looking for the development of new drugs and thus increasing the demand for protein stability analysis techniques. Due to an increase in government funding, research institutes are involved heavily in discovering new diseases and therapies and therefore helping this market to grow.

Global Protein Stability Analysis Market Definition

Proteins are called the building blocks of an organism. Protein stability is vital as it determines the functionality and active state of the proteins. Proteins can be derived as stable, active, and efficient when they are folded properly. Whereas, during unfavorable conditions, they unfold and hence get inactivate. The protein stability analysis assists to determine the stability of proteins in a sample. There are various methods and techniques available to determine protein stability. This analysis is carried out by biotechnological and pharmaceutical industries for drug development and by research and academic institutes. Moreover, protein stability can be determined through chromatography, High-Performance Liquid Chromatography (HPLC), Surface Plasma Resonance (SPR), Spectroscopy, Differential Scanning Calorimeter (DSC). The Protein Stability Analysis Market is primarily fuelled by the growing adoption of open innovation models in pharmaceutical & biotechnology companies and increasing pharmaceutical outsourcing. Moreover, an emerging economy will provide new growth opportunities for players in the market.

Global Protein stability analysis Market Overview

The Protein Stability Analysis market is expected to drive due to the upsurging number of recombinant protein therapeutics and developing pharmaceutical outsourcing across the globe. Protein Stability is one of the fundamental properties that affect organ and body function, activity, and regulation of biomolecules within a body. In addition to this, protein stability changes are majorly found in the form of mutated proteins which are significantly involved in several disease prevalences. Stability predictors computationally predict protein–stability changes caused by mutations. Thus, the need for protein-based therapeutics has been increased over the past couple of decades. On the other hand, therapeutic proteins are produced by recombinant DNA technology that includes recombinant hormones, interferons, interleukins, hematopoietic growth factors, tumor necrosis factors, blood-clotting factors, thrombolytic drugs, enzymes, monoclonal antibodies vaccines, and many others. These proteins majorly lead to the majority of severe diseases. Thus, the need for protein stability analysis has increased significantly.

Moreover, over the past couple of decades, there has been a significant trend among pharmaceutical manufacturers and service providers to upsurge the outsourcing of research and developments, drug discovery, and manufacturing of pharmaceutical products and techniques such as protein stability analysis, recombinant protein therapeutics, and many others. Since it is one of the effective ways of reducing capital costs and gaining access to capacity and capabilities that might not be available in-house. Thus, leading to a substantial increase in the adoption of pharmaceutical outsourcing. However, the lack of skilled medical professional protein stability equipment manufacturing, as well as respective research and developments, has significantly limited the growth of the Protein Stability Analysis Market growth.

Global Protein Stability Analysis MarketSegmentation Analysis

The Global Protein Stability Analysis Market is segmented on the basis of Product, Technique, End-User, and Geography.

Protein Stability Analysis Market, By Product

• Reagents and Assay Kits
• Instruments
• Consumables and Accessories
• Software

On the basis of Product, the market has been segmented into Reagents and Assay Kits, Instruments, Consumables and Accessories, and Software. Reagents and Assay Kits accounted for the largest market share and are projected to grow at the highest CAGR of 11.05% during the forecast period. The market share held by the Reagents and Assay Kits segment is attributed to the elevated use of these products and the cost-effectiveness associated with its use as compared to other types of products.

Protein Stability Analysis Market, By Technique

• Chromatography
• Spectroscopy
• Surface Plasmon Resonance

Based on Technique, the market is bifurcated into Chromatography, Spectroscopy, and Surface Plasmon Resonance. Chromatography accounted for the largest market share and is projected to grow at the highest CAGR of 10.89% during the forecast period. Chromatography is one of the most accurate and sensitive techniques for the isolation and purification of proteins when compared to its counterparts. Various companies are hence focusing on commercializing new products based on this technology in order to expand their product portfolio. Chromatography is an important biophysical technique that enables the separation, identification, and purification of the components of a mixture for qualitative and quantitative analysis.

Protein Stability Analysis Market, By End-User

• Pharmaceutical and Biotechnological Companies
• Contract Research Organizations
• Academic and Government Institutes

Based on End-User, the market has been segmented into Pharmaceutical and Biotechnological Companies, Contract Research Organizations, and Academic and Government Institutes. Pharmaceutical and Biotechnological Companies accounted for the largest market share and is projected to grow at the highest CAGR of 11.32% during the forecast period. The growth of the Protein Stability Analysis Market is primarily driven by the growing adoption of open innovation models in pharmaceutical & biotechnology companies and increasing pharmaceutical outsourcing. Emerging economies will provide new growth opportunities for players in the market. However, the high cost of protein stability analysis systems is expected to restrain the growth of this market to a certain extent.

Protein Stability Analysis Market, By Geography

• North America
• Europe
• Asia Pacific
• Rest of the world

On the basis of Geographical Analysis, the market is classified into North America, Europe, Asia Pacific, and the Rest of the world. North America accounted for the largest market share and is projected to grow at a CAGR of 10.33% during the forecast period. North America is further expected to dominate the global market due to the growing adoption of technically advanced products in the countries of this region. This growth is attributed owing to increasing awareness among individuals regarding the use of advanced healthcare gadgets in the region. Moreover, the United States and Canada have a developed and well-structured health care system that encourages research and development and drug discovery efforts thereby promoting the growth of the Protein Stability Analysis Market.

Key Players

The “Global Protein Stability Analysis Market” study report will provide valuable insight with an emphasis on the global market.  The major key players in the market are Agilent Technologies Inc., Enzo Biochem Inc., GE Healthcare, Shimadzu Corporation, Thermo Fisher Scientific, Horiba Ltd., NanoTemper Technologies, and Waters Corporation.

The competitive landscape section also includes key development strategies, market share, and market ranking analysis of the above-mentioned players globally. 

Key Developments

• Thermo Fisher Scientific Acquired PPD, Inc., a Leading Clinical Research Organization. The acquisition Offers both meaningful cost and revenue synergies which will further accelerate growth
• Agilent Technologies Inc has acquired Resolution Bioscience, a healthcare research company specializing in NGS technology, molecular biology, cancer diagnostics, and more.

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• Qualitative and quantitative analysis of the market based on segmentation involving both economic as well as non-economic factors• Provision of market value (USD Billion) data for each segment and sub-segment• Indicates the region and segment that is expected to witness the fastest growth as well as to dominate the market• Analysis by geography highlighting the consumption of the product/service in the region as well as indicating the factors that are affecting the market within each region• Competitive landscape which incorporates the market ranking of the major players, along with new service/product launches, partnerships, business expansions, and acquisitions in the past five years of companies profiled• Extensive company profiles comprising of company overview, company insights, product benchmarking, and SWOT analysis for the major market players• The current as well as the future market outlook of the industry with respect to recent developments which involve growth opportunities and drivers as well as challenges and restraints of both emerging as well as developed regions• Includes in-depth analysis of the market of various perspectives through Porter’s five forces analysis• Provides insight into the market through Value Chain• Market dynamics scenario, along with growth opportunities of the market in the years to come• 6-month post-sales analyst support

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