In 2021, the pharmaceutical industry in China generated a total operating revenue of more than USD 45 billion.
Mevalonic acid is a molecule that plays a crucial role in the biosynthesis of isoprenoids, which are a diverse class of natural products that have a wide range of biological activities. Isoprenoids include important molecules such as sterols, carotenoids, and quinones, which are essential components of many biological processes, including cellular respiration, photosynthesis, and hormone synthesis. Mevalonic acid is a 6-carbon molecule with the chemical formula C6H12O4. It is synthesized in the cytoplasm of eukaryotic cells from acetyl-CoA through a series of enzymatic reactions catalyzed by the enzyme HMG-CoA reductase. This process is the first committed step in the biosynthesis of isoprenoids, which are then further modified to produce a wide variety of compounds with diverse functions. Mevalonic acid is a key intermediate in the biosynthesis of cholesterol, which is an essential component of cell membranes and a precursor for the synthesis of many hormones. Inhibition of HMG-CoA reductase, the enzyme that catalyzes the synthesis of mevalonic acid, is a common strategy for the treatment of hypercholesterolemia and other related disorders.
Mevalonic acid is also a precursor for the synthesis of coenzyme Q10, which is a vital component of the electron transport chain in mitochondria, the organelles responsible for producing energy in eukaryotic cells. Coenzyme Q10 is also a potent antioxidant and has been shown to have a wide range of beneficial effects on human health. In addition to its role in the biosynthesis of cholesterol and coenzyme Q10, mevalonic acid is also a precursor for the synthesis of a variety of other isoprenoids, including isopentenyl pyrophosphate (IPP) and dimethylallyl pyrophosphate (DMAPP). These molecules are essential building blocks for the synthesis of a wide variety of natural products, including carotenoids, chlorophyll, and vitamin E.
Mevalonic acid is also used in the cosmetic industry to produce compounds such as squalene, which is widely used in skin care products due to its moisturizing properties. The demand for squalene is expected to grow in the coming years due to increasing consumer awareness about the benefits of natural and organic ingredients in cosmetic products.
Global Mevalonic acid market is expected to grow in the coming years due to increasing demand for isoprenoids in various industries, particularly in the pharmaceutical and cosmetic industries. The Asia-Pacific region is expected to be the fastest-growing market for mevalonic acid due to the presence of a large number of manufacturers in the region. The key players in the market are primarily focused on expanding their production capacity to meet the growing demand for mevalonic acid in various industries.
Download Free Sample ReportIncreasing Demand for Isoprenoids and Growing Cosmetic Industry are Driving Market Growth8
Mevalonic acid is primarily used as a precursor for the synthesis of a variety of isoprenoids, which are widely used in the pharmaceutical industry to treat a variety of diseases, such as cardiovascular diseases, cancer, and neurodegenerative diseases, among others. The demand for isoprenoids in the pharmaceutical industry is expected to increase in the coming years due to the growing prevalence of these diseases and the increasing focus on research and development in the pharmaceutical industry.
Mevalonic acid is also used in the cosmetic industry to produce compounds such as squalene, which is widely used in skin care products due to its moisturizing properties. The demand for squalene is expected to grow in the coming years due to increasing consumer awareness about the benefits of natural and organic ingredients in cosmetic products. As a result, the demand for mevalonic acid in the cosmetic industry is also expected to increase in the coming years.
Rising Demand from Emerging Economies is Driving Market Growth
Emerging economies such as China and India are expected to be significant markets for mevalonic acid due to the growing demand for isoprenoids in various industries in these countries. The increasing focus on research and development in the pharmaceutical industry and the growing demand for natural and organic ingredients in cosmetic products are expected to drive the demand for mevalonic acid in these countries.
Mevalonic acid is used as a precursor for the synthesis of carotenoids, which are widely used in the food industry as food colorants and antioxidants. The expansion of the food industry, particularly in emerging economies, is expected to drive the demand for carotenoids, which in turn is expected to increase the demand for mevalonic acid in the coming years.
Major Challenges faced by Mevalonic Acid Market
Mevalonic acid is primarily produced through fermentation, which requires significant investment in infrastructure and equipment. The high production costs associated with mevalonic acid production can affect the overall profitability of the industry. In addition, the cost of raw materials, such as glucose and yeast extract, can also affect the production cost of mevalonic acid.
The yield of mevalonic acid production through fermentation is relatively low, which can affect the overall production efficiency of the industry. Low yield can result in high production costs and reduced profitability. As a result, the industry is focused on developing new and improved strains of microorganisms that can produce mevalonic acid more efficiently.
Mevalonic acid industry is subject to various regulations related to the use of the compound in different industries, such as the pharmaceutical and cosmetic industries. Compliance with these regulations can be challenging and can result in additional costs for the industry. In addition, changes in regulations can affect the demand for mevalonic acid in different industries, making it challenging for companies to plan their production accordingly.
Although mevalonic acid is used as a precursor for the synthesis of isoprenoids, its applications are limited to specific industries such as the pharmaceutical and cosmetic industries. As a result, the demand for mevalonic acid is concentrated in a few industries, which can affect the overall growth of the market.
Recent Trends and Developments
- Mevalonic acid isa key intermediate in the biosynthesis of isoprenoids, which are important forthe production of cholesterol, hormones, and other essential compounds in thehuman body. In the last three years, there has been an increased demand formevalonic acid in the pharmaceutical industry, where it is used as a startingmaterial for the synthesis of drugs such as statins and bisphosphonates. Thedemand for these drugs is expected to continue to grow in the coming years,which is expected to drive the growth of the mevalonic acid market.
- Mevalonic acidindustry has been focusing on developing new and improved strains ofmicroorganisms that can produce mevalonic acid more efficiently andcost-effectively. In the last three years, there have been several advancementsin mevalonic acid production technology, including the use of metabolicengineering to improve the yield of mevalonic acid production. Theseadvancements have led to the development of new and improved strains ofmicroorganisms that can produce mevalonic acid more efficiently and cost-effectively.
- There has been agrowing demand for natural and sustainable products in the last few years,which has opened up new opportunities for the global mevalonic acid market.Mevalonic acid can be produced through fermentation using sugar and corn starch,making it a sustainable alternative to synthetic alternatives. As a result, thedemand for mevalonic acid in industries such as the cosmetic and foodindustries is expected to continue growing.
- Several investorshave been investing in the mevalonic acid market in the last three years, whichis expected to drive the growth of the industry. For instance, in 2021, EvonikIndustries announced that it had invested in a biotechnology company called In Ovo,which is focused on developing new strains of microorganisms for the productionof mevalonic acid. This investment is expected to enable Evonik to expand itsmevalonic acid production capacity and meet the growing demand for thecompound.
Market Segmentation
Global Mevalonic Acid Market
Market Players
Sigma-Aldrich Chemicals Private Limited, Tlc Pharmaceutical Standards Ltd, Carbosynth Ltd., Tocris Bioscience, TCI Chemicals, Cayman Chemical Company, Santa Cruz Biotechnology, Inc., Adooq Bioscience are some of the key players in the Global Mevalonic Acid Market.
Attribute | Details |
Base Year | 2022 |
Historic Data | 2018 – 2021 |
Estimated Year | 2023 |
Forecast Period | 2024 – 2028 |
Quantitative Units | Revenue in USD Million, Volume in Units, and CAGR for 2018-2022 and 2023-2028 |
Report coverage | Revenue forecast, volume forecast, company share, competitive landscape, growth factors, and trends |
Segments covered | Application |
Regional scope | North America, Europe, Asia-Pacific, South America, Middle East & Africa |
Country scope | United States, Mexico, Canada, France, Germany, United Kingdom, Spain, Italy, China, India, South Korea, Japan, Australia, Brazil, Argentina, Colombia, South Africa, Saudi Arabia, UAE |
Key companies profiled | Sigma-Aldrich Chemicals Private Limited, Tlc Pharmaceutical Standards Ltd, Carbosynth Ltd., Tocris Bioscience, TCI Chemicals, Cayman Chemical Company, Santa Cruz Biotechnology, Inc., Adooq Bioscience |
Customization scope | 10% free report customization with purchase. Addition or alteration to country, regional & segment scope. |
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Delivery Format | PDF and Excel through Email (We can also provide the editable version of the report in PPT/Word format on special request) |