Cell Penetrating Peptide Market - Global Industry Size, Share, Trends, Opportunity, and Forecast, 2018-2028, Segmented By Type (Protein-based CPPs, Peptide-based CPPs), By Application (Drug Delivery, Gene Delivery, Diagnostics, Molecular Imaging, Others (Vaccine development, Antimicrobial Therapy), By End User (Pharmaceutical and Biotechnology Companies, Contract Research Organizations (CROs), Hos
Published Date: November - 2024 | Publisher: MIR | No of Pages: 320 | Industry: Healthcare | Format: Report available in PDF / Excel Format
View Details Buy Now 2890 Download Sample Ask for Discount Request CustomizationCell Penetrating Peptide Market - Global Industry Size, Share, Trends, Opportunity, and Forecast, 2018-2028, Segmented By Type (Protein-based CPPs, Peptide-based CPPs), By Application (Drug Delivery, Gene Delivery, Diagnostics, Molecular Imaging, Others (Vaccine development, Antimicrobial Therapy), By End User (Pharmaceutical and Biotechnology Companies, Contract Research Organizations (CROs), Hos
| Forecast Period | 2024-2028 |
| Market Size (2022) | USD 133.33 Million |
| CAGR (2023-2028) | 9.47% |
| Fastest Growing Segment | Process chromatography |
| Largest Market | North America |
Market Overview
Global Cell Penetrating Peptide Market has valued at USD 133.33 Million in 2022 and is anticipated to grow at an impressive rate of around 9.47% in the forecast period, 2024-2028. Cell-penetrating peptides (CPPs) are a class of peptides that were identified as being capable of transporting the molecules they are linked with across cellular membranes. Therefore, a promising approach for enhancing the permeability of therapeutic proteins and peptides across cellular membranes is by attaching them to a CPP.
Key Market Drivers
Rising Demand for Targeted Drug Delivery
Targeted drug delivery is gaining traction for its ability to enhance treatment efficacy, reduce side effects, and improve patient outcomes. This demand is closely intertwined with the capabilities of CPPs, making them a crucial element in fulfilling the promise of precise and personalized medicine.
Advancements in Peptide Synthesis and Modification
Peptide synthesis and modification methods have evolved significantly in recent years, enabling researchers to design and engineer CPPs with enhanced properties and functionalities.
Rising Incidence of Chronic Diseases
The rising prevalence of chronic diseases, such as cancer, cardiovascular disorders, neurodegenerative conditions, and diabetes, has spurred significant interest in developing targeted and effective treatment strategies.
Key Market Challenges
Efficiency and Specificity of Delivery
The efficiency of CPP-mediated delivery can vary significantly across different cell types. Achieving consistent and reliable uptake of therapeutic cargoes across diverse cell lines is a complex task. Researchers must optimize CPP sequences and cargoes for each specific cell type of interest, which can be time-consuming and resource-intensive.
Cost and Scalability of Production
The production of CPPs often involves intricate synthesis processes and chemical modifications. These processes can be time-consuming and require specialized expertise, contributing to higher production costs. Streamlining and optimizing these processes are essential to reduce manufacturing expenses.
Key Market Trends
Advancements in Peptide Engineering
Advancements in peptide engineering enable the creation of CPPs with specific cellular uptake mechanisms. Researchers can design CPPs that interact favorably with certain types of cells, optimizing cellular uptake efficiency and enhancing the overall efficacy of drug delivery.
Combination Therapies
Combining CPPs with other therapeutic agents, such as chemotherapy drugs or biologics, can lead to enhanced treatment efficacy. CPPs facilitate the intracellular delivery of these agents, ensuring that they reach their intended targets in sufficient concentrations.
Segmental Insights
Type
Based on the Type, the Protein Based CPPs segment is anticipated to witness substantial market growth throughout the forecast period. This growth can be attributed to multiple factors, such as Peptide-based CPPs, with their inherent cell-penetrating properties, facilitate the efficient delivery of various therapeutic agents into target cells. This enhanced cellular uptake capability opens up new possibilities for drug delivery, gene therapy, and diagnostics.
End Use Insights
Based on the end-use segment, the Pharmaceutical and Biotechnology Companies segment has been the dominant force in the market. Pharmaceutical and biotechnology companies are investing substantial resources in researching the potential of CPPs as innovative drug delivery systems. Their investment drives the discovery of novel CPP sequences, modification strategies, and cargo delivery mechanisms.
Regional Insights
North America, specifically the Cell Penetrating Peptide Market, dominated the market in 2022, primarily due to North America, particularly the United States, is a hub for cutting-edge scientific research and innovation. Leading research institutions, universities, and biotechnology companies in the region are driving advancements in CPP technologies, design, and applications.
Recent Developments
- In January 2022, Novo Nordisk India launched the world’s first‘Peptide In A Pill’ for diabetes management. The peptide named, Semaglutide, aGLP-1 receptor analog (GLP-1 RA), is one of the drug classes for the managementof type 2 diabetes.
- In May 2022, the United States Food and DrugAdministration approved Mounjaro (tirzepatide) injection to improve blood sugarcontrol in adults with type 2 diabetes, as an addition to diet and exercise.Mounjaro is a type of drug called a dual glucose-dependent insulinotropicpolypeptide (GIP) and glucagon-like peptide-1 (GLP-1) receptor agonist.
- In June 2022, Evonik launched a new peptide toboost the productivity of cell-culture-based biopharmaceuticals. cQrex AC is achemically defined and highly soluble source of L-cystine that enables asufficient supply of this key amino acid to cells.
Key Market Players
- The Cupid PeptideCompany.
- AltaBioscienceLtd.
- AnaSpec Inc.
- Peptomyc.
- Amidebio LLC
- Biopeptide Co LLC
- AAPPTec
- CSBio Company Inc
- CEM Corporation
- Bachem Holding AG
| By Type | By Application | By End User | By Region |
| Protein-based CPPs Peptide-based CPPs | Drug Delivery Gene Delivery Diagnostics Molecular Imaging Others | Pharmaceutical and Biotechnology Companies Contract Research Organizations (CROs) Hospitals and Clinics | North America Europe Asia Pacific South America Middle East & Africa |
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