Preparative and Process Chromatography Market - Global Industry Size, Share, Trends, Opportunity, and Forecast, Segmented By Product (Process Chromatography, Preparative Chromatography), By Type (Liquid Chromatography, Gas Chromatography, Thin Layer Chromatography, Paper Chromatography, Gel-permeation Chromatography, Hydrophobic Interaction Chromatography), By End-use (Food, Nutraceutical, Others)
Published Date: November - 2024 | Publisher: MIR | No of Pages: 320 | Industry: Healthcare | Format: Report available in PDF / Excel Format
View Details Buy Now 2890 Download Sample Ask for Discount Request CustomizationPreparative and Process Chromatography Market - Global Industry Size, Share, Trends, Opportunity, and Forecast, Segmented By Product (Process Chromatography, Preparative Chromatography), By Type (Liquid Chromatography, Gas Chromatography, Thin Layer Chromatography, Paper Chromatography, Gel-permeation Chromatography, Hydrophobic Interaction Chromatography), By End-use (Food, Nutraceutical, Others)
| Forecast Period | 2018-2028 |
| Market Size (2023) | USD 8.91 Billion |
| CAGR (2023-2028) | 7.18% |
| Fastest Growing Segment | Process chromatography |
| Largest Market | North America |
Market Overview
Global Preparative and Process Chromatography Market has valued at USD 8.91 Billion in 2022 and is anticipated to project robust growth in the forecast period with a CAGR of 7.18% through 2028. Chromatography is a process for separating constituents or solutes of a mixture based on the relative quantities of each solute dispersed between a moving fluid stream, known as the mobile phase, and a contiguous stationary phase. The method of preparative chromatography is used to separate components of complicated mixtures. In the pharmaceutical sector, it is used to clear molecules of contaminants, and the molecules are then refined and employed for a variety of purposes, such as clinical supply in the case of active medicinal components. Process chromatography is an analytical method that allows for on-line separation and quantification of mixture components in a chemical process. On-line chromatographic analyzers can function in a continuous and automated mode, taking a set number of samples, separating the chemical components using adsorption or partitioning columns, and then detecting concentration of each using a detector.
Key Market Drivers
Rising Demand for Biopharmaceuticals
The rising demand for biopharmaceuticals has a significant influence on the growth of the global preparative and process chromatography market. Preparative and process chromatography are essential techniques used in the purification and separation of biomolecules, including biopharmaceuticals such as proteins, antibodies, vaccines, and other complex molecules.
Increasing Food and Beverage Quality Standards
The increasing food and beverage quality standards have a notable influence on the growth of the global preparative and process chromatography market. Chromatography techniques, including preparative and process chromatography, play a crucial role in ensuring the safety, quality, and compliance of food and beverage products.
Growing Research and Development Activities
Growing research and development (R&D) activities have a significant influence on the growth of the global preparative and process chromatography market. Preparative and process chromatography techniques play a crucial role in various research and development processes across industries. In the pharmaceutical industry, chromatography is essential for isolating and purifying potential drug compounds during the early stages of drug discovery. As R&D efforts continue to expand to identify new therapeutics, the demand for chromatography techniques increases to ensure the production of pure and high-quality compounds for testing and evaluation.
Key Market Challenges
The complexity of Method Development
Developing effective chromatography methods involves optimization of various parameters, such as column selection, mobile phase composition, flow rates, and detection conditions. This process can be time-consuming and resource-intensive, requiring significant investments in expertise, equipment, and consumables. The complexity and length of method development can discourage organizations from adopting chromatography techniques.
Competition and Market Fragmentation
Competition encourages companies to continuously innovate and develop new technologies, products, and solutions. This leads to the introduction of advanced chromatography systems, columns, resins, and software that improve separation efficiency, scalability, and ease of use.
Key Market Trends
Advancements in Column Technologies
New column packing materials, stationary phases, and geometries are designed to provide higher separation efficiencies. This leads to better resolution, shorter analysis times, and increased productivity in both analytical and preparative chromatography applications.
Advanced Data Analytics
Data analytics enable real-time monitoring and analysis of chromatography processes. By analyzing data from chromatography runs, manufacturers can identify trends, anomalies, and optimization opportunities to enhance separation efficiency, reduce cycle times, and improve overall process productivity.
Segmental Insights
Type
Based on the Type, the liquid chromatography segment is anticipated to witness substantial market growth throughout the forecast period. This growth can be attributed to multiple factors, such as widespread application across several industries. Bioactive compounds are isolated from a variety of sources using different variations of this approach. Liquid chromatography plays a critical function in guaranteeing product quality during the production process.
End Use Insights
Based on the end-use segment, the pharmaceutical segment has been the dominant force in the market. The high usage of preparative and process chromatography in drug safety assessment and The demand for the development of an effective vaccine against the novel coronavirus in a reduced timeframe has led to the introduction of unique vaccine strategies, such as viral vector-based vaccines, nucleic acid-based vaccines, and virus-like particle vaccines. Pharmaceutical companies heavily rely on preparative and process chromatography for drug discovery, development, and production. Chromatography is used to purify and separate active pharmaceutical ingredients (APIs), intermediates, and final drug products, ensuring high-quality and pure compounds.
Regional Insights
North America, specifically the Preparative and Process Chromatography Market, dominated the market in 2022, primarily due to North America is home to a robust biopharmaceutical industry with a large number of pharmaceutical and biotechnology companies. These companies heavily rely on preparative and process chromatography for the purification and separation of biomolecules, such as proteins and antibodies, used in drug development and production.
Recent Developments
- In January 2022, RotaChrom Technologies NA,the developer of first industrial-scale Centrifugal Partition Chromatography(CPC) technology platform, announced the formation of a strategic partnershipwith Red Mesa Science & Refining, LLC. The two teams will collaborateclosely on method development, sharing and optimizing existing procedures,while also collaborating to develop new and profitable applications employingRotaChrom's centrifugal chromatography technology.
- In July 2021, Danaher-owned Cytiva and Pallintended to invest a total of USD 1.5 billion to expand 13 locations in theUnited States, Europe, and Asia. The investment initiative focuses on goodsused in the production of biologic medications. The companies will investaround USD 600 million in chromatography resins, including a new plant in theUnited States, and approximately USD 400 million in cell culture mediummanufacturing.
- In April 2021, Tosoh Bioscience GmbH, aproducer of chromatographic solutions for biomolecule separation, announced thelaunch of their TSKgel FcR-IIIA-5PW HPLC column. This column is the second inTosoh Corporation's independent FcRaffinity chromatography portfolio forantibody drug analysis.
Key Market Players
- GE Healthcare.
- Danaher Corporation
- Merck KGaA
- Bio-Rad Laboratories Inc.
- Thermo Fisher Scientific Inc.
- Shimadzu Corporation
- Agilent Technologies
- Waters Corporation
- Novasep Holding S.A.S
- Sartourius AG.
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