Peripheral Blood Mononuclear Cells Market - Global Industry Size, Share, Trends, Opportunity, and Forecast, 2018-2028, Segmented By Product (Cryopreserved or Frozen PBMC, Cultured or Fresh PBMC, and Peripheral Blood Mononuclear Cell Isolation & Viability Kits), By Application (Immunology, Hematology, Infectious Disease, Hematology, and Others), By Techniques (Density Gradient Centrifugation, Leuka
Published Date: November - 2024 | Publisher: MIR | No of Pages: 320 | Industry: Healthcare | Format: Report available in PDF / Excel Format
View Details Buy Now 2890 Download Sample Ask for Discount Request CustomizationPeripheral Blood Mononuclear Cells Market - Global Industry Size, Share, Trends, Opportunity, and Forecast, 2018-2028, Segmented By Product (Cryopreserved or Frozen PBMC, Cultured or Fresh PBMC, and Peripheral Blood Mononuclear Cell Isolation & Viability Kits), By Application (Immunology, Hematology, Infectious Disease, Hematology, and Others), By Techniques (Density Gradient Centrifugation, Leuka
Global peripheral blood mononuclear cells market was valued at USD 235.68 million in 2022 and is anticipated to grow at a CAGR of 10.39%, during the period, 2023-2028 owing to rising rate in number of cell therapies, high demand of research and development for toxicology testing and reaction mechanism of the compound responsible for new and stable development of products. For instance, in June 2023, a study published in National Library of Medicine, it assessed the immune response of peripheral blood mononuclear cells (PBMC) that were infected in vitro with the Colombian strain (Col) of Trypanosoma cruzi and treated with Benzonidazole.
Peripheral blood mononuclear cells (PBMCs) are a type of blood cell that plays a crucial role in the immune system. PBMCs are a heterogeneous population of cells that are isolated from the peripheral blood, which is the blood circulating throughout the body. They are composed of lymphocytes, monocytes, and other immune cells. Lymphocytes are a type of white blood cell that includes T cells, B cells, and natural killer (NK) cells. T cells are responsible for cell-mediated immune responses, B cells produce antibodies for humoral immune responses, and NK cells are involved in the innate immune system and killing infected or cancerous cells. Monocytes are another type of white blood cell that circulate in the bloodstream and can differentiate into macrophages or dendritic cells when they migrate into tissues. Macrophages are responsible for engulfing and destroying foreign substances, dead cells, and cellular debris, while dendritic cells play a critical role in initiating and regulating immune responses by presenting antigens to T cells. The isolation and characterization of PBMCs have revolutionized the understanding of the immune system and have contributed to advancements in various fields, including cancer research, infectious diseases, autoimmune disorders, and transplantation medicine.
PBMCs are widely used in various research applications, including immunology, cell therapy, vaccine development, and drug discovery. They provide valuable insights into immune responses, allow researchers to study various immune cell populations, and serve as a source of cells for cell-based therapies. PBMCs can be isolated from peripheral blood using techniques such as density gradient centrifugation or specialized cell separation methods.
Additionally, the rise in number of cell therapies, expansion in research & development schemes, increasing focus of key players on R&D in peripheral blood mononuclear cells, increasing focus on regenerative medicine, as well as an increase in demand for cell operations among the population, increasing investigation of various aspects of immunology, infectious diseases, autoimmune disorders, transplantation, and vaccine development are projected to provide market players with lucrative prospects in the future.
Growing Advancement for Toxicology Research
For instance, according to the clinicaltirals.gov.in, 972 studies are carried out for peripheral blood mononuclear cells.
Increasing Importance of Peripheral Blood Mononuclear Cells for Cell Therapy
For instance, according to the Centers for Disease Control and Prevention, around 37,300 new cases of HPV+ tumour occurs each year in the U.S., accounting for 3% of all malignancies in women and 2% of all cancers in men. With increasing prevalence of HPV in the country, companies are continuously focusing on the development of therapy and drugs to enter the US market
Also, the Adoptive Cell Transfer (ACT) is a type of cell therapy that involves the transfer of immune cells, typically T cells, into patients to target and eliminate diseases, such as cancers. PBMCs are often used as a starting material to isolate and expand specific subsets of T cells, such as tumor-infiltrating lymphocytes (TILs), tumor-associated antigen-specific T cells, or genetically engineered T cells. PBMCs provide a convenient source of T cells for ACT therapies.
Growing Investment in Research & Development for Human Well-Being
Rapid advancements in research and development (R&D) practices and activities are propelling the growth of the market as novel cell/gene therapies/medications and new products are developed for the treatment of fatal diseases. PBMCs are a reasonable way to acquire physiologically relevant (immune) proteins from routinely collected blood samples, and they do so without the native human plasma's well-known analytical challenges brought on by the presence of highly abundant proteins for driving the growth of the market. Furthermore, the government of different countries for their growth in healthcare sector are providing funds for the ongoing research of peripheral blood mononuclear cells.
Additionally, the growing awareness of the potential of PBMCs in disease research has led to increased R&D activities and contribute to market growth. PBMCs play a crucial role in drug discovery and development. They are utilized in early-stage research to assess the efficacy and safety of potential drug candidates. PBMCs provide a human-relevant model for studying immune responses and evaluating the effects of new compounds on immune cells. The growing awareness of the value of PBMCs in drug discovery has resulted in increased demand and utilization of these cells, driving the growth of the PBMCs market. The awareness of the therapeutic potential of cell-based therapies has been growing rapidly. PBMCs are essential in the development and manufacturing of cell-based therapies, such as adoptive cell transfer, CAR-T cell therapy, and immunotherapies. The therapeutic benefits of these advanced therapies, coupled with the increasing awareness of PBMCs' role in their development, have led to significant R&D efforts and the growth of global peripheral blood mononuclear cells market. There has been a notable increase in collaboration between academic institutions, research organizations, and the biopharmaceutical industry. This collaboration has fostered knowledge exchange, joint research projects, and funding initiatives focused on the application of PBMCs in various areas of research. The growing awareness of the potential of PBMCs and the collaborative efforts in R&D have positively impacted the growth of global peripheral blood mononuclear cells market.
Market Segmentation
The global peripheral blood mononuclear cells market is segmented based on product, application, technique, source, region, and competitive landscape. Based on product, the market can be split into cryopreserved or frozen PBMC cultured or fresh PBMC, and peripheral blood mononuclear cell isolation & viability kits. Based on application, the market can be divided into immunology, hematology, infectious disease, and others. Based on techniques, the market is divided into density gradient centrifugation, leukapheresis, and others. In terms of source, the market can be categorized into human and animals.
Company Profiles
Charles River Laboratories International, Inc., Lonza Group AG, Corning Inc, Bio-Rad Laboratories Inc, ABCAM, Biolegend Inc, ZEN-Bio Inc, DAPCEL, Inc., Creative Bioarray, iXCells Biotechnologies USA, LLC, Miltenyi Biotec B.V. & CO. KG, STEMCELL Technologies Inc., Precision Medicine Group, LLC, StemExpress, LLC, RayBiotech Life, Inc., REPROCELL Inc., Cytologics LLC, BioIVT LLC, Biopredic International, and Cell Applications, Inc. etc. are among the major players in the global peripheral blood mononuclear cells market.
| Attribute | Details |
| Market size value in FY2022 | USD 235.68 Million |
| Revenue Forecast in FY2028 | USD 420.98 Million |
| Growth Rate | 10.39% |
| Base Year | 2022 |
| Historical Years | 2018 – 2028 |
| Estimated Year | 2023 |
| Forecast Period | 2024 – 2028 |
| Quantitative Units | Revenue in USD Million, and CAGR for 2018-2022 and 2023-2028 |
| Report Coverage | Revenue forecast, company share, competitive landscape, growth factors, and trends |
| Segments Covered | Product Application Technique Source |
| Regional Scope | North America; Europe; Asia Pacific; South America; Middle East & Africa |
| Key Companies Profiled | Charles River Laboratories International, Inc., Lonza Group AG, Corning Inc, Bio-Rad Laboratories Inc, ABCAM, Biolegend Inc, ZEN-Bio Inc, DAPCEL, Inc., Creative Bioarray, iXCells Biotechnologies USA, LLC, Miltenyi Biotec B.V. & CO. KG, STEMCELL Technologies Inc., Precision Medicine Group, LLC, StemExpress, LLC, RayBiotech Life, Inc., REPROCELL Inc., Cytologics LLC, BioIVT LLC, Biopredic International, Cell Applications, Inc. |
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