DNA Synthesis Market Size - By Service (Oligonucleotide Synthesis, Gene Synthesis), Method (Solid Phase, PCR-Based), Application (Research & Development, Therapeutic), End-use (Academic & Research Institutes, Biopharmaceutical), Forecast 2024 - 2032

Published Date: August - 2024 | Publisher: MIR | No of Pages: 240 | Industry: Healthcare | Format: Report available in PDF / Excel Format

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DNA Synthesis Market Size - By Service (Oligonucleotide Synthesis, Gene Synthesis), Method (Solid Phase, PCR-Based), Application (Research & Development, Therapeutic), End-use (Academic & Research Institutes, Biopharmaceutical), Forecast 2024 - 2032

DNA Synthesis Market size

DNA Synthesis Market size was valued at USD 4.1 billion in 2023 and is expected to register a CAGR of 19.5% between 2024 and 2032. The growth of the market can be attributed to the growing demand for DNA synthesis for its utility in molecular biology, genetic engineering, and clinical diagnostics & therapeutics.
 

DNA Synthesis Market

Rising disease burden globally coupled with growing demand for research in drug discovery and personalized medicine is positively impacting the market growth. Further, several technological advancements in the field of DNA synthesis and genomics in recent years, high R&D investments, and advanced services offered by market players are some major factors that will drive the market growth over the analysis period.
 

DNA synthesis is the process of artificially creating DNA molecules. It involves chemically synthesizing nucleotide sequences in the laboratory, that can be used for various applications such as genetic engineering, research, and biotechnology.
 

COVID-19 Impact

The COVID-19 pandemic disrupted the healthcare system worldwide, owing to strict lockdown and restrictions on transportation of raw materials that caused disruptions in the overall global supply chain. The initial phase of the pandemic observed a slight slowdown in some non-COVID-19-related research activities that rely on DNA synthesis. However, the COVID-19 pandemic positively impacted the DNA synthesis market growth at the later stage of the year. DNA synthesis played major role for the development of COVID-19 diagnostic tests and vaccines. Additionally, significant role of DNA synthesis in various aspects of research and development related to COVID-19 highlighted the importance of DNA synthesis in medical research for the development of new therapies, thereby positively influencing the overall market growth for the coming years.

DNA Synthesis Market Trends

Companies are pouring more money into creating DNA in labs as the realms of synthetic biology and genetic engineering continue to expand. This investment has been soaring in recent years. And this cash infusion will only help the market grow even faster, especially as companies research new technologies. For example, Molecular Assemblies got $25.8 million from Casdin Capital in 2021 to work on better ways to make DNA with enzymes. And in March 2021, Twist Bioscience announced that Casdin Capital, Fidelity Management & Research Company, and Viking Global Investors had given them $100 million to improve their DNA-making platform. So, with all this money going into the DNA synthesis business, you can bet that the market is going to keep getting bigger and better.

DNA Synthesis Market Restraint

DNA is like a powerful tool that can be used for good or bad. To make sure it's used safely, governments have put in place strict rules and guidelines. These rules help prevent people from using DNA to create harmful things or to do bad stuff. DNA has huge potential to change the world, especially in medicine, farming, and science. But it's also important to be careful because it could also be used to make bad things like dangerous diseases or weapons. So, governments require scientists and companies that work with DNA to get licenses and register with them. They might also need to report what they're doing with DNA, like what types they're making, why they're doing it, and how much they're making. While these strict rules help keep us safe, they can also slow down the progress of research and companies that work with DNA.

DNA Synthesis Market Analysis

DNA Synthesis Market, By Service, 2021 - 2032 (USD Billion)

DNA synthesis is mainly divided into two typescreating short pieces of DNA (oligonucleotide synthesis) and larger sections (gene synthesis). In 2022, oligonucleotide synthesis was the bigger part of the market, accounting for over half (52.6%) of the revenue. This is largely due to the growing field of synthetic biology, which uses DNA to create new biological systems. Oligonucleotides are essential for this, as well as for DNA sequencing and genetic engineering. These techniques are driving advancements in medicine and biotechnology. Companies are also investing in new oligonucleotide products. For example, Bachem recently partnered with Eli Lilly to develop and produce drugs based on oligonucleotides. These types of initiatives are expected to keep the oligonucleotide synthesis segment growing strong.

DNA Synthesis Market, By Method (2023)

Imagine you want to build a DNA molecule, the blueprint for life. There are three main ways to do it, just like there are different ways to build a house. The most popular method is like building a house from bricks. You start with a solid foundation and add DNA building blocks one by one, creating custom molecules with specific sequences and modifications. This method is precise, flexible, and quick, like a well-oiled factory. It's also easy to scale up, so you can build larger DNA molecules as needed. In 2022, this solid phase synthesis method dominated the DNA building market, accounting for over 36% of the business. Experts predict it will continue to grow rapidly in the years to come. That's because it gives researchers the power to design and build DNA molecules with pinpoint accuracy and speed, making it a valuable tool for everything from medical research to gene therapy.

The DNA synthesis industry has three main areasresearch, diagnostics, and medicine. In 2022, research was the biggest part of the industry, making up 43.6%. This is because DNA synthesis is a key tool for biotech research, like finding new drugs. It's also used to make tests for genetic diseases, infections, and cancer. For example, in 2021, DNAScript got a $2.2 million grant to develop printers that can print DNA. So, because DNA synthesis is so useful in research and has so many applications, the industry is expected to grow.

DNA synthesis is a vital technique that's widely used in different fields, including academia, research, and the biopharmaceutical industry. Research labs and universities are expected to spend over 11 billion dollars on DNA synthesis by 2032. This is because DNA synthesis is a key tool in their research. It allows scientists to create custom-made DNA, which is essential for studying genes and developing new treatments. DNA synthesis is especially useful for studying complex biological processes. It gives researchers the power to create DNA sequences that are difficult or impossible to obtain using traditional cloning methods. As a result, DNA synthesis is revolutionizing molecular biology research and leading to exciting new discoveries and breakthroughs.

North America DNA Synthesis Market, 2020 – 2032 (USD Million)

North America is the undisputed leader in the global DNA synthesis market, with a whopping 38.4% of the revenue pie in 2022. This huge chunk of the market is no coincidence, but the result of major investments in research and development (R&D) and the presence of key players in the region. Governments in North America are also doing their part to fuel growth by launching initiatives and encouraging collaborations between companies. A good example is the partnership between DNA Script and Moderna, Inc. in April 2021. Thanks to a $5 million grant from the U.S. Defense Advanced Research Projects Agency, they teamed up to create a prototype for quickly producing vaccines and treatments on the go. The icing on the cake is the increasing number of chronic and infectious diseases, as well as the growing demand for more effective ways to diagnose and treat them. All these factors are expected to keep the North American DNA synthesis market thriving.

DNA Synthesis Market Share

Major market players operating in the DNA synthesis market include

  • Thermo Fisher Scientific, Inc.
  • Twist Bioscience
  • Bioneer Corporation
  • Eton Bioscience
  • LGC Biosearch Technologies
  • IBA GmbH
  • Eurofins Scientific
  • Integrated DNA Technologies, Inc.
  • Quintara Biosciences
  • GenScript Biotech Corporation
  • OriGene Technologies, Inc.
  • Eurogentec
  • ProMab Biotechnologies
  • BIOMATIK
  • ProteoGenix
  • BOSTER antibody
  • ELISA experts

These industry players majorly adopt various strategies including collaborations, acquisitions, mergers, and partnerships to create a global footprint and sustain market competition.
 

DNA Synthesis Industry News

  • In May 2023, GenScript Biotech Corporation launched its GenTitan Gene Fragments Synthesis service to expedite gene synthesis at lower cost. This is expected to help the company widen its service offerings and cater to a larger customer base.
     
  • In January 2023, Twist Bioscience and Astellas entered into a multitarget antibody discovery research collaboration. This strategic collaboration aimed to discover antibodies against multiple targets of interest and curative therapies for patients suffering from diseases that lack treatment options. This strategy is expected to help the company to enhance its service offerings.
     

The DNA synthesis market research report includes an in-depth coverage of the industry with estimates & forecast in terms of revenue in USD from 2018 to 2032, for the following segments

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By Service

  • Oligonucleotide synthesis
    • Standard oligonucleotide synthesis
    • Custom oligonucleotide synthesis
  • Gene synthesis
    • Custom gene synthesis
    • Gene library synthesis

By Method

  • Solid phase synthesis
  • PCR-based enzyme synthesis 
  • CHIP-based DNA synthesis

By Application

  • Research and Development
  • Diagnostics
  • Therapeutics

By End Use

  • Biopharmaceutical companies
  • Academic and research institutes
  • Contract research organizations

The above information is provided for the following regions and countries

  • North America
    • U.S.
    • Canada
  • Europe
    • Germany
    • UK
    • France
    • Spain
    • Italy
    • Rest of Europe
  • Asia Pacific
    • Japan
    • China
    • India
    • Australia
    • South Korea
    • Rest of Asia Pacific
  • Latin America
    • Brazil
    • Mexico
    • Rest of Latin America
  • Middle East & Africa
    • South Africa
    • Saudi Arabia
    • Rest of Middle East & Africa

 

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