Cell Dissociation Market Size - By Product (Enzymatic Dissociation, Non-Enzymatic Dissociation), Application (Tissue Dissociation, Cell Detachment), End-user, Global Forecast, 2023 - 2032

Published Date: July - 2024 | Publisher: MIR | No of Pages: 240 | Industry: Healthcare | Format: Report available in PDF / Excel Format

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Cell Dissociation Market Size - By Product (Enzymatic Dissociation, Non-Enzymatic Dissociation), Application (Tissue Dissociation, Cell Detachment), End-user, Global Forecast, 2023 - 2032

Cell Dissociation Market Size

Cell Dissociation Market size was valued to be USD 378.3 million in 2022 and is expected to reach USD 1.6 billion in 2032, growing at a CAGR of 15.3% by 2032 driven by the rising focus on the development of cell-based therapeutics that has led to the development of patient-specific cell therapies.

 

Cell Dissociation Market

Cell dissociation is essential for isolating and culturing cells. Also, there is a notable increase in interest and investment in cell-based research. Government, private firms, and biotechnology companies are dedicating substantial resources to support cell therapy technologies in areas such as stem cell biology, regenerative medicine, and immunotherapy. For instance, the U.S. National Institutes of Health (NIH) allocate significant funds around a billion dollars per year to support stem cell research. Additionally, collaborations and partnerships between academia and industry are common, facilitating research translation.

 

Cell dissociation refers to the process of separating and isolating individual cells or cell clusters from a tissue, organ, or cell culture. This process typically involves breaking down cell-to-cell and cell-to-substrate adhesions to release the constituent cells, allowing them to be suspended as individual entities in a solution.

 

COVID-19 Impact

Hey there! You won't believe how the pandemic has actually boosted the business of separating cells in the lab. Even though lockdowns and social distancing made things tough, scientists found ways to keep working together and even do experiments from home. Thanks to the tools available for separating cells, some research actually kept going, even though everyone was spread out. The big push to create vaccines and treatments for COVID-19 made scientists even more excited to experiment. Separating cells was like the secret weapon for finding out how to make vaccines, check if they worked, and create those super-targeted antibodies. And because they needed to find drugs to fight COVID-19, they used cells to test out potential candidates.

 

Cell Dissociation Market Driving Factors

The increasing focus on the development of cell-based therapeutics is a significant driver for the industry. Cell-based therapeutics, also known as cell therapies or regenerative medicine, involve the use of living cells to treat diseases, repair damaged tissues, and restore normal cellular function in patients. Cell dissociation is a critical step in the process of expanding cells for therapy. Researchers and manufacturers rely on effective dissociation techniques to isolate, culture, and expand cells to therapeutic numbers. Also, regenerative medicine often relies on tissue engineering approaches to create functional tissues and organs for transplantation.

 

Cell Dissociation Restraint

The game-changing potential of cell dissociation techniques is undeniable, but the cost can be a real hurdle. Many researchers rely on grants and funding from different groups like government agencies, charities, and businesses to make their projects happen. Plus, the equipment and materials needed for cell dissociation aren't cheap either. Scientists and institutions need to set aside a big chunk of their money to buy, care for, and replace these things. Safety, quality, and how well cell-based treatments work are also big concerns. To make sure these treatments are safe and effective, researchers need to have strict quality control and testing. These extra steps can add even more to the cost because they require specialized testing and meeting all the rules and regulations.

 

Cell Dissociation Market Analysis

Cell Dissociation Market Size, By Product, 2021 - 2032 (USD Million)

When it comes to separating cells from each other or from their surroundings, there are a few different ways to go about it. One way is to use Enzymes, which are special proteins that can break down the connections between cells. The other way is to use non-enzymatic methods, which don't use Enzymes at all. And finally, there are instruments and accessories that can help with the cell dissociation process. Among the enzymatic methods, trypsin is the most widely used enzyme for dissociating cells. It's known for its efficiency in breaking down the bonds between cells, making it a good choice for routine cell separation tasks. Other Enzymes like collagenase, elastase, papain, hyaluronidase, and DNase can also be used, depending on the specific cell types and tissues being worked with. The non-enzymatic methods typically use chemical or physical forces to separate cells. These methods are often gentler than enzymatic methods and can be used with more sensitive cell types. The market for cell dissociation products is divided into these three segmentsenzymatic dissociation, non-enzymatic dissociation, and instruments & accessories. In 2022, the enzymatic dissociation segment was the largest, accounting for nearly half of the market share. This is because Enzymes are highly effective and versatile, making them suitable for a wide range of cell types and applications. They can also be scaled up for large-scale cell culture and bioprocessing applications, which is important for producing cell-based therapies and other biologics.

 

Cell Dissociation Market Revenue Share, By Application, (2022)

Imagine a puzzle made of tiny pieces, each representing a different type of cell. To understand how this puzzle fits together, scientists need to break it down into smaller pieces. That's where cell dissociation comes in. The cell dissociation market is split into two main groupstissue dissociation and cell detachment. Tissue dissociation is like taking apart puzzle pieces that are stuck together, while cell detachment is separating individual pieces. In 2022, the tissue dissociation market was the bigger one, and it's expected to keep growing until it's worth about $842 million by 2032. That's because tissue dissociation is useful in so many areas of science. Scientists use tissue dissociation in cell biology, immunology, neuroscience, cancer research, and even developing new medicines. They need to break down tissues to study specific cell types within them. Drug companies use tissue dissociation to test how potential new medicines work on different types of cells and tissues. This helps them find new medicines faster. Tissue dissociation is also used to get cells for studying genes and proteins, which helps us better understand diseases and develop treatments.

 

Depending on who's using them, cell dissociation products are sold to companies that make medicine and do biotechnology research, universities and other places that do research, companies that do clinical research for other companies (CROs), and others. Drug companies are expected to be the biggest buyers, growing by about 15.6% each year until 2032. That's because these companies are always looking for new drugs and cures. They use cell dissociation to test out new drugs, figure out how diseases work, and make sure their drugs are safe and effective. Drug companies also use cell dissociation to make cell lines bigger, keep bioreactors running smoothly, get cells for making medicine, and find and get ready special cells like stem cells and immune cells that can be used to treat patients. They also use these products to find cells from specific patients for research and to make new treatments, especially for cancer and rare diseases.

 

North America Cell Dissociation Market Size, 2020 – 2032 (USD Million)

In 2022, the United States and Canada led the way in the business of taking cells apart, with a whopping 37.2% of the global market. This is mainly because the government has been giving it a thumbs up, and there are a ton of pharmaceutical and biotech companies in the region. These companies use taking cells apart a lot for things like testing new drugs, making medicines, and developing cell-based treatments. Startup biotech companies and well-established giants in North America are also at the top of their game when it comes to research. This pushes the adoption of cutting-edge methods for taking cells apart. Plus, companies in this region are known for being quick to embrace the latest technology and tools for their research. They're always ready to jump on anything that makes taking cells apart more efficient, precise, and good for the cells.

 

Cell Dissociation Market Share

Market players operating in the cell dissociation is as mentioned below

  • Merck KGaA
  • Thermo Fisher Scientific
  • Danaher Corp
  • STEMCELL Technologies
  • Sartorius AG
  • Miltenyi Biotec
  • PAN-Biotech
  • HiMedia Laboratories
  • F. Hoffmann-La Roche Ltd
  • S2 Genomics, Inc.
  • Nuromics.

In the cell dissociation market, market share is influenced by several key factors. For instance, Thermo Fisher Scientific, a prominent player in this field, maintains a robust market share due to its extensive product portfolio and continuous innovation. Their high-quality dissociation products are trusted by researchers worldwide, enhancing their brand reputation. Thermo Fisher's effective distribution networks and strategic partnerships ensure a broad customer reach. Also, their adherence to stringent regulatory standards, like Good Manufacturing Practices (GMP), adds to their credibility.
 

Cell Dissociation Market Industry News

  • In March 2023, Agilent Technologies Inc. announced the acquisition of e-MSion, an early-stage company behind the innovative electron capture dissociation (ECD) technology known as the ExD cell. This helped the company widen their product offerings.
     
  • In October 2022, Thermo Fisher Scientific launched closed and automated cell isolation and bead removal solution to help evolve cell therapy manufacturing. This helped to improve cell purity, dissociation efficiency, and increased recovery of target cells for scalable cell therapy manufacturing.
     

The cell dissociation market report includes an in-depth coverage of the industry with estimates & forecast in terms of revenue in USD Million from 2018 to 2032 for the following segments

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By Product

  • Enzymatic dissociation
    • Trypsin
    • Collagenase
    • Elastase
    • Papain
    • Hyaluronidase
    • DNase
    • Other enzymes
  • Non-enzymatic dissociation
  • Instruments & accessories

By Application

  • Tissue dissociation
  • Cell detachment

By End-user

  • Pharmaceuticals and biotechnology companies
  • Research and academic institutes
  • CROs
  • Other end-users

The above information is provided for the following regions and countries

  • North America 
    • U.S.
    • Canada
  • Europe 
    • Germany
    • UK
    • France
    • Spain
    • Italy
    • Rest of Europe
  • Asia Pacific 
    • China
    • Japan
    • India
    • Australia
    • Rest of Asia Pacific
  • Latin America 
    • Brazil
    • Mexico
    • Rest of Latin America
  • Middle East & Africa 
    • South Africa
    • Saudi Arabia
    • Rest of Middle East & Africa

 

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