Protein Engineering Market Size
Protein Engineering Market size was valued at over USD 2.5 billion in 2023 and is estimated to grow at 15.9% CAGR from 2024 to 2032 due to the growing collaborations and partnerships for fostering innovations and advancements in the field.

Researchers and biotech firms are pooling resources and expertise to develop novel techniques for protein modification and designs. This ongoing synergy among industry stakeholders is promising to transform drug discovery and biotechnology leading to the creation of new therapeutics and diagnostics with improved efficacy and specificity for benefiting patients worldwide. For instance, in March 2024, BRAIN Biotech and AMSilk collaborated on protein engineering for enhancing structural proteins for performance materials. This partnership marked the first patent application, showcasing BRAIN Biotech's reliance on protein engineering and bioinformatics for rational protein design.
The rising frequency of protein-deficient disorders, such as marasmus and kwashiorkor especially in developing and underdeveloped countries, is also increasing the demand for protein engineering. Scientists are continually developing novel protein-based therapies to combat these conditions while focusing to provide effective treatment options for the affected population.
Protein Engineering Market Report Attributes
Report Attribute |
Details |
Base Year | 2023 |
---|
Protein Engineering Market Size in 2023 | USD 2.5 Billion |
---|
Forecast Period | 2024 – 2032 |
---|
Forecast Period 2024 – 2032 CAGR | 15.9% |
---|
2024 – 2032 Value Projection | USD 9.3 Billion |
---|
Historical Data for | 2018 – 2023 |
---|
No. of Pages | 155 |
---|
Tables, Charts & Figures | 276 |
Segments covered | Product, Technology, Protein Type, End-use, and Region |
---|
Growth Drivers | - Rising prevalence of protein-deficient diseases
- Increase in adoption of protein drugs over non-protein drugs
- Increasing research & development activities in the biopharmaceutical industry
- Growing funding opportunities for protein engineering
|
---|
Pitfalls & Challenges | - High costs of protein engineering techniques
- Limited availability of qualified researchers
|
---|
Protein engineering is becoming super important for fixing protein-related diseases because it allows us to design better medicines that work better and are easier to get. Scientists are working hard to make these treatments more affordable so that people all over the world can benefit. For example, in May 2023, the United Nations Children's Fund (UNICEF) reported that nearly half of all deaths in children under 5 are caused by not getting enough to eat. This shows how important protein engineering is for making food-related solutions to fight malnutrition and potentially save the lives of children everywhere.
However, the high development costs and limited clinical validation may hinder the market progress to some extent. Researchers are seeking innovative funding models and conducting ongoing trials to address these challenges. In addition, collaborations between academia, industry, and regulatory bodies will play a vital role in reducing costs and enhancing validation processes, ultimately facilitating the translation of protein engineering research into clinical applications.
Protein Engineering Market Trends
In recent years, governments around the world have significantly increased their involvement in driving technological progress, particularly in the field of biotechnology. This surge in government support has been instrumental in funding research and development (R&D) projects aimed at combating protein-deficient disorders. Scientists and policymakers are joining forces to develop cutting-edge therapies and preventive measures that utilize proteins to effectively combat these disorders. Governments are recognizing the crucial role they play in fostering innovation in this area by providing funding and support. This concerted effort is not only a testament to our dedication to improving global health outcomes but also a direct response to addressing the underlying causes of protein deficiency. By investing in this research, governments are paving the way for the development of more effective and accessible treatments for malnutrition-related diseases. A prime example of this is the Japanese government's investment in AI research. This initiative has enabled the emergence of innovative biotechnology companies like RevolKa, which employs machine learning to accelerate protein engineering and enhance the efficiency of protein-based therapies.
Protein Engineering Market Analysis
Based on product, the reagents segment may exhibit 16.2% CAGR through 2032. Reagents play a crucial role in protein engineering, with researchers continuously refining and developing new ones. These substances enable the manipulation and modification of proteins for various applications from drug development to biotechnology. Subsequently, advancements in reagent technology will further enhance the precision and efficiency of protein engineering processes, further opening new possibilities for therapeutic interventions and scientific discoveries in fields, such as personalized medicine and biomaterials engineering.

In terms of technology, the protein engineering market size from the rational protein design segment is expected to reach over USD 6.15 billion by 2032. This expansion is due to the growing prominence of rational protein design as a cornerstone of protein engineering, with scientists applying computational methods to predict and optimize protein structures and functions. This approach is allowing the creation of novel proteins with desired properties for specific applications, such as drug development and biocatalysis.
Moreover, ongoing advancements in computational algorithms and molecular modeling techniques will continue to refine rational protein design for enabling the generation of tailor-made proteins with enhanced performance and functionality, thus driving innovation in diverse fields ranging from medicine to materials science.
The market for making proteins is expected to grow quickly, especially in the area of monoclonal antibodies. This is because scientists are making these antibodies better for use in targeted treatments, tests, and vaccines for diseases like cancer and problems with the immune system. Also, they are making monoclonal antibodies more precise, powerful, and safe. This means that treatments will be more effective and tailored to each person, and precision medicine will become more common, with monoclonal antibodies playing a key role in improving how patients do.
Based on end-use, the market value from the pharmaceutical & biotechnology segment is predicted to record over USD 4.19 billion by 2032. This is due to the rising protein engineering advancements in pharmaceuticals and biotechnology for continuously improving drug development and biotech applications. Scientists are manipulating protein structures for enhancing their functions and designing novel molecules for therapeutic purposes. Researchers are also employing cutting-edge technologies to engineer proteins with unprecedented precision for opening new avenues for tackling diseases and improving human health.

North America protein engineering market is predicted to record more than USD 3.75 billion by 2032 due to the notable shift towards sustainable and green technologies in the region. Companies are investing in R&D to develop eco-friendly processes for protein engineering. Additionally, there is a rising focus on personalized medicine as healthcare providers are increasingly tailoring treatments to individual patients based on genetic makeup and other factors. Multiple regional firms are also increasingly integrating sustainable practices into protein engineering processes and advancing personalized medicine approaches to provide more targeted and effective treatments for patients.
Protein Engineering Market Share
These industry players are developing innovative technologies as well as products and are continuously investing in R&D and expanding their portfolios to meet the evolving market demands. They are also indulging in partnership ventures to widen their global presence and customer base.
Protein Engineering Market Companies
Some of the major protein engineering industry players are
- Agilent Technologies, Inc.
- Amgen Inc.
- Bio-Rad Laboratories, Inc.
- Bristol Myers Squibb Company
- Bruker Corporation
- Danaher Corporation
- Genentech, Inc.
- Integrated DNA Technologies, Inc.
- Lonza Group
- Merck KGaA
- Thermo Fisher Scientific Inc.
- Vertex Pharmaceuticals Incorporated
Protein Engineering Industry News
- In April 2023, Adaptyv Biosystems inaugurated a protein engineering foundry for introducing innovative tools for swift and cost-effective validation of AI-designed proteins.
- In July 2022, Amgen partnered with Generate Biomedicines to discover and advance protein therapies for five clinical targets across diverse therapeutic areas. The collaboration included a USD 50 million upfront payment for positioning Amgen competitively.
Protein engineering market research report includes an in-depth coverage of the industry with estimates & forecast in terms of revenue in USD Million from 2018 to 2032 for the following segments
Click here to Buy Section of this Report
Market, By Product
- Instruments
- Reagents
- Software & services
Market, By Technology
- Irrational protein design
- Rational protein design
Market, By Protein Type
- Insulin
- Monoclonal antibodies
- Vaccines
- Growth factors
- Coagulation factors
- Interferon
- Other protein types
Market, By End-use
- Academic research institutes
- Contract research organizations (CROs)
- Pharmaceutical & biotechnology companies
The above information is provided for the following regions and countries
- North America
- Europe
- Germany
- UK
- France
- Italy
- Spain
- Rest of Europe
- Asia Pacific
- China
- Japan
- India
- Australia
- South Korea
- Rest of Asia Pacific
- Latin America
- Brazil
- Mexico
- Argentina
- Rest of Latin America
- Middle East and Africa
- South Africa
- Saudi Arabia
- UAE
- Rest of Middle East and Africa