Antiemetics Drugs Market - By Drug Type (Serotonin-Receptor Antagonists, Glucocorticoids, Anticholinergics, Dopamine Receptor Antagonists), Application (CINV, Gastroenteritis), Route of Administration, Distribution Channel – Global Forecast 2024 – 2032

Antiemetics Drugs Market - By Drug Type (Serotonin-Receptor Antagonists, Glucocorticoids, Anticholinergics, Dopamine Receptor Antagonists), Application (CINV, Gastroenteritis), Route of Administration, Distribution Channel – Global Forecast 2024 – 2032

Antiemetics Drugs Market Size

Antiemetics Drugs Market size was valued at around USD 6.7 billion in 2023 and is estimated to grow at 5.6% CAGR from 2024 to 2032. Antiemetic drugs are medications used to prevent or alleviate nausea and vomiting. These symptoms can be caused by a variety of conditions, including motion sickness, gastrointestinal disorders, pregnancy, chemotherapy, radiation therapy, surgery, and certain medications. Antiemetic drugs work through different mechanisms to target the pathways in the brain and gastrointestinal tract that trigger nausea and vomiting.

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The rising prevalence of nausea and vomiting-inducing conditions is a significant driver for the antiemetic drugs market. Conditions such as chemotherapy-induced nausea and vomiting (CINV), post-operative nausea and vomiting (PONV), and nausea associated with pregnancy are becoming more prevalent globally, impacting patient quality of life and increasing the demand for effective antiemetic medications. For instance, according to the American Association for Cancer Research, approximately 1,958,310 new cases of cancer were diagnosed in the U.S. in 2023, with an estimated 609,820 deaths attributed to the disease. This growing incidence of cancer, coupled with the increasing use of chemotherapy and radiation treatments worldwide, is expected to significantly boost the demand for antiemetics.

Furthermore, the growing availability of reimbursement and coverage for antiemetic drugs further propels market growth. As healthcare systems and insurance providers increasingly recognize the importance of managing nausea and vomiting, reimbursement policies are expanding to include more antiemetic medications. This increased access lowers financial barriers for patients, driving higher utilization rates and market expansion.
 

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Antiemetics Drugs Market Trends

• Advancements in drug formulations also play a crucial role in shaping the market. Pharmaceutical companies are investing in research and development to innovate new formulations that offer improved efficacy, safety, and patient compliance.
   
• From extended-release formulations to novel drug delivery systems, these advancements not only enhance treatment outcomes but also differentiate products in a competitive market landscape.

Antiemetics Drugs Market Analysis

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Based on drug type, the market is divided into serotonin-receptor antagonists, anticholinergics, glucocorticoids, dopamine receptor antagonists, neurokinin receptor antagonists, antihistamines, and other drug types. The serotonin-receptor antagonists segment of the antiemetics drugs market is forecasted to reach USD 3.4 billion by 2032.

• These drugs, which include well-known medications such as ondansetron and granisetron, are highly effective in preventing and treating nausea and vomiting associated with chemotherapy, radiotherapy, and surgery.
• Their mechanism of action, which involves blocking serotonin receptors in the brain and gastrointestinal tract, makes them particularly effective in managing severe and persistent nausea and vomiting.
• Additionally, ongoing advancements in drug formulations, such as extended-release versions and novel delivery systems, enhance patient compliance and convenience, further driving market growth.

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Based on application, the antiemetics drugs market is bifurcated into chemotherapy induced nausea and vomiting (CINV), gastroenteritis, postoperative nausea and vomiting (PONV), and other applications. The chemotherapy induced nausea and vomiting (CINV) segment accounted for USD 3.1 billion in 2023 primarily due to the high incidence of cancer and the critical need for effective management of chemotherapy-induced nausea and vomiting (CINV).

• Chemotherapy is a cornerstone of cancer treatment but often causes severe nausea and vomiting, significantly impacting patient quality of life and treatment adherence. This necessitates the use of antiemetic drugs to alleviate these debilitating side effects.
• Additionally, advancements in cancer treatments, including new chemotherapeutic agents and combination therapies, have increased the demand for potent and reliable antiemetics.
• The increasing number of cancer diagnoses and the subsequent rise in chemotherapy treatments globally further drive the substantial market share of the chemotherapy induced nausea and vomiting (CINV) segment in the market.

Based on route of administration, the antiemetics drugs market is bifurcated into oral, parenteral, and other routes of administration. The oral segment accounted for USD 4.1 billion in 2023.

• Oral antiemetics offer a convenient and non-invasive method of administration, which enhances patient compliance, particularly for those undergoing prolonged treatment regimens such as chemotherapy or post-operative care.
• Additionally, the widespread availability and variety of oral formulations cater to diverse patient needs, from pediatric to geriatric populations. The efficacy and ease of storage and transportation of oral medications further bolster their popularity.
• Furthermore, advancements in oral drug delivery systems, such as rapid-dissolve tablets and extended-release formulations, have improved the therapeutic outcomes and patient experience, driving the preference for oral antiemetics in the market.

Based on distribution channel, the antiemetics drugs market is bifurcated into hospital pharmacies, retail pharmacies, and online pharmacies. The hospital pharmacies segment accounted for USD 3.4 billion in 2023.

• Hospital pharmacies are integral in managing severe cases of nausea and vomiting, especially those associated with chemotherapy, surgery, and other intensive medical treatments.
• The centralized nature of hospital pharmacies ensures that patients receive timely and efficient access to antiemetic medications, often as part of comprehensive inpatient care.
• Moreover, the presence of specialized healthcare professionals in hospital settings allows for personalized and closely monitored treatment regimens, which is crucial for managing complex medical conditions. This high level of patient care and the necessity for immediate availability of medications in critical situations contribute to the significant revenue generated by hospital pharmacies in the market.

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The growth of the antiemetics drugs market in the U.S., projected to reach USD 4.2 billion by 2032.

• Continuous research and development efforts in the U.S. have led to the introduction of more effective and safer antiemetic drugs.
• Innovations in drug formulations and delivery systems, such as extended-release formulations and transdermal drug delivery systems which is estimated to reach USD 61 billion by 2032, enhance patient compliance and efficacy, thereby driving market growth.

The antiemetics drugs market in UK is expected to experience significant and promising growth from 2024 to 2032.

• The prevalence of chronic diseases, particularly cancer and gastrointestinal disorders, is on the rise in the UK. Cancer remains a leading cause of morbidity, necessitating chemotherapy and radiation treatments that often induce nausea and vomiting. For instance, according to estimates from Macmillan Cancer Support, the number of individuals living with cancer in the UK is projected to increase steadily surpassing 3.5 million by 2025, reaching 4 million by 2030, and expected to reach 5.3 million by 2040.
• Antiemetic drugs play a pivotal role in managing these treatment-related side effects, thereby driving their demand in clinical practice.

Japan antiemetics drugs market is anticipated to witness lucrative growth between 2024 – 2032.

• The Japanese government supports healthcare initiatives aimed at improving cancer care and enhancing patient outcomes. Policies promoting early detection, diagnosis, and treatment of cancer contribute to increased demand for antiemetic drugs as part of comprehensive cancer management strategies.

The antiemetics drugs market in Saudi Arabia is expected to experience significant and promising growth from 2024 to 2032.

• The country's economic growth and substantial healthcare spending support the expansion of the pharmaceutical market, including antiemetic drugs. Increased healthcare investments facilitate the adoption of innovative treatments and technologies, benefiting both patients and healthcare providers.

Antiemetics Drugs Market Share

The antiemetics drugs industry is characterized by intense competition, involving both major global companies and smaller to medium-sized companies vying for market dominance. Key to market strategy is the consistent launch of innovative products utilizing various technologies. Major industry leaders play a significant role in driving innovation by making substantial investments in research and development. Moreover, strategic partnerships, acquisitions, and mergers play crucial roles in strengthening market positions and enhancing international presence.

Antiemetics Drugs Market Companies

Some of the eminent market participants operating in the antiemetics drugs industry include

• Astellas Pharma Inc.
• Baxter International Inc.
• Cipla Limited
• Eagle Pharmaceuticals, Inc.
• Glenmark Pharmaceuticals Limited
• GSK plc
• Hikma Pharmaceuticals PLC
• Johnson & Johnson
• Merck & Co., Inc.
• Novartis AG
• Pfizer Inc.
• Takeda Pharmaceutical Company Limited
• Teva Pharmaceutical Industries Limited
• Torrent Pharmaceuticals Limited
• Viatris Inc.

Antiemetics Drugs Industry News

• In January 2023, Glenmark Pharmaceuticals Ltd introduced AKYNZEO I.V., an intravenous injection formulation, under an exclusive licensing agreement with Helsinn, a Swiss biopharma group. AKYNZEO I.V. is designed to prevent chemotherapy-induced nausea and vomiting (CINV). It combines fosnetupitant (235 mg) and palonosetron (0.25 mg) in a fixed dose, available as a ready-to-dilute I.V. injection. This launch has expanded the company's product portfolio significantly and positioned it competitively in the market.
• In June 2022, Eagle Pharmaceuticals, Inc. acquired Acacia Pharma Group plc under the UK's Companies Act 2006, adding BARHEMSYS and BYFAVO—both FDA-approved chemical entities with robust patent protection to its portfolio. BARHEMSYS stands out as the first FDA-approved antiemetic for rescuing patients from postoperative nausea and vomiting (PONV) despite prior prophylaxis, enhancing Eagle's product offerings and revenue potential significantly.

The antiemetics drugs market research report includes an in-depth coverage of the industry with estimates & forecast in terms of revenue in USD Million from 2021 – 2032 for the following segments

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Market, By Drug Type

• Serotonin-receptor antagonists
• Anticholinergics
• Glucocorticoids
• Dopamine receptor antagonists
• Neurokinin receptor antagonists
• Antihistamines
• Other drug types 

Market, By Application

• Chemotherapy induced nausea and vomiting (CINV)
• Gastroenteritis
• Postoperative nausea and vomiting (PONV)
• Other applications  

Market, By Route of Administration

• Oral
• Parenteral
• Other routes of administration

Market, By Distribution Channel

• Hospital pharmacies
• Retail pharmacies
• Online pharmacies

The above information is provided for the following regions and countries

• North America 
  • U.S.
  • Canada 
• Europe 
  • Germany
  • UK
  • France
  • Spain
  • Italy
  • Netherlands
  • Rest of Europe 
• Asia Pacific
  • China
  • Japan
  • India
  • Australia
  • South Korea
  • Rest of Asia Pacific 
• Latin America
  • Brazil
  • Mexico
  • Argentina
  • Rest of Latin America 
• Middle East and Africa 
  • South Africa
  • Saudi Arabia
  • UAE
  • Rest of Middle East and Africa