Animal Model Market Size - Animal Type (Mice, Rats, Fish, Birds), Technology (CRISPR, Microinjection), Application (Research & Development), Use (Human, Veterinary), End-use, (Companies, Contract Research Organizations), Forecast 2023 – 2032

Published Date: July - 2024 | Publisher: MIR | No of Pages: 240 | Industry: Animal Health and Nutrition | Format: Report available in PDF / Excel Format

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Animal Model Market Size

Animal Model Market size was valued at USD 19.4 billion in 2022 and is estimated to progress at significant growth rate of 6.9% over the analysis timeframe. High growth of the market can be attributed to several factors such as rising adoption of animal models for biomedical research, surging expenditure & high investments in dug development & discover, growing focus on precision medicine, and extensive applications of animal models in healthcare industry.

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As per the U.S. government statistics, in 2021, the number of laboratory animals employed in biomedical research were around more than 797,546, with a 2.2% surge as compared to 2019 and 2020. These statistics exclude the number of mice, rats, and fish models that are being used, which further adds up the number of animal models used for research.

Animal model can be defined as a non-human, living, genetically engineered animal that is used for scientific research purpose and investigation of human diseases. Also, these animal models are used for the purpose of better understanding of the human disease process without harming an actual human.

 

Animal Model Market Report Attributes
Report Attribute Details
Base Year 2022
Animal Model Market Size in 2022 USD 19.4 Billion
Forecast Period 2023 to 2032
Forecast Period 2023 to 2032 CAGR 6.9%
2032 Value Projection USD 38.4 Billion
Historical Data for 2018 to 2022
No. of Pages 704
Tables, Charts & Figures 1,006
Segments covered Animal Type, Technology, Application, Use, End-use, and Region
Growth Drivers
  • Growing number of pharmaceutical research and development activities
  • Increasing application areas of animal models across different research areas
  • Physiological similarities between human and animal reduces drug development time
  • Emergence of CRISPR as a powerful tool in the field of biomedical research
  • Growing consumption of personalized medicine driving the demand for humanized mice models
Pitfalls & Challenges
  • High maintenance cost of animal models
  • Strict regulations and guidelines
  • Growing opposition on animal testing by several organizations

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COVID-19 Impact

The emergence of COVID-19 was an unprecedented public health concern that has positively impacted the animal model market. Healthcare sector was also largely affected by the increasing prevalence of COVID-19 cases. However, heavy investments in research activities related to COVID-19 and the increased funding towards R&D activities to innovate novel therapeutics have promoted the use of animal models despite the pandemic.

Several pharmaceutical, biotechnology companies, and clinical research organizations revised their R&D spending to increase clinical trials to focus on the pandemic. Numerous animal models have been studied and employed to study COVID-19 infection. Mice were profoundly employed in infectious disease studies, especially SARS-CoV-2 strain adapted mice after deliberate passaging of virus in lung tissues. Due to such aforementioned factor, a positive impact was observed during the COVID-19 pandemic.

Animal Model Market Trends

The increasing number of pharmaceutical research and development activities is anticipated to drive the market progress. Need for novel drugs to help meet the unmet medical requirements are amongst the key value drivers of research-based pharmaceutical & biotechnology companies. The pharmaceutical sector develops several novel drugs that offer valuable clinical benefits. The surging number of investments by government as well as private players are amongst the prime variables driving the number of pharmaceutical research and development activities.

For instance, according to the Congressional Budget Office, in 2019, the pharmaceutical sector spent USD 83 billion in R&D activities. These expenditures comprises a comprehensive spectrum of activities, such as discovering & testing novel medications and testing for safety-parameters or regulatory purposes.

Animal Model Market Restraint

Animal experiments are heavily regulated around the world to protect animals and ensure they're treated ethically. Each country has specific rules called regulatory guidelines that researchers must follow. Before they can use animals in their studies, researchers have to prove that they have a good reason to do so and that the benefits outweigh any harm to the animals. They also have to show that there are no other ways to study the same thing without using animals. Once a researcher's plan is approved, it's reviewed by a special committee called an IACUC (Institutional Animal Care and Use Committee). This committee makes sure that the study is designed in a way that treats the animals humanely and minimizes their suffering. These regulations are important to make sure that animals are treated well in research, but they can also make it harder for researchers to do their work. This can slow down the development of new medical treatments and cures.

Animal Model Market Analysis

By animal type, the animal model market is classified into mice, rats, fish, birds, cattle’s, pigs, amphibians, guinea pigs, dogs, cats, rabbits, monkey’s, sheep, hamsters, and other animal types. The mice segment dominated the market in 2022 with approximately 49.2% business share. Mice model is amongst the most common animal model used in studying human disease and human health. High phylogenetic similarities and physiological relatedness to humans, low maintenance, ease of breeding them in the laboratory, and easy availability of a number of inbred strains make mice models most predominantly used for research of human biology and disease.

Further, mice have a relatively short reproductive cycle and lifespan. This characteristic enables researchers to study multiple generations of mice in a relatively short period. Thus, several advantages offered by mice animal model is set to drive the segment trends.

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Animal models are important tools for studying human diseases and developing new treatments. These models can be created using different technologies, including CRISPR, microinjection, embryonic stem cell injection, and nuclear transfer. CRISPR is a powerful new technology that makes it easier than ever to edit the genes of animals. This technology has led to the development of a wide range of new animal models that are more accurate and easier to use than traditional models. CRISPR has revolutionized the field of animal model research. It has made it possible to create animals with more precise genetic modifications, which has led to a better understanding of human diseases and the development of new therapies. Here's how CRISPR worksScientists use CRISPR to make a small cut in the DNA at the desired location. The cell then uses its own DNA repair machinery to fix the cut. Scientists can design the CRISPR system to insert or delete specific genes, or to change the sequence of genes. CRISPR is still a relatively new technology, but it has already had a major impact on animal model research. It is likely to continue to play a major role in the development of new therapies for human diseases.

Based on application, the animal model market is segmented into research & development, production & quality control, academics, preclinical applications and other applications. The research & development segment held majority market share in 2022 and is expected to witness notable growth to reach USD 22.1 billion by 2032. The increasing number of research & development projects and rise in the investments to develop novel therapeutics is set to drive the segment share. Animal models are used to feature some of the earliest developments related with the disease and to detect potential drug targets.

Further, the pharmacokinetic and pharmacodynamic experiments are conducted for evaluating gastrointestinal absorption, distribution, metabolism, and drug excretion (ADME) parameters for every drug candidate. Animal models are extensively employed in these ADME studies that aid in screening these drug candidates to move forward to the next step in safety and efficacy studies.

Based on use, the animal model market is segmented into human and veterinary. The human segment accounted for largest revenue share in 2022 and is anticipated to grow at significant 7.0% growth rate during the analysis period. This significant segmental revenue is majorly attributed to the increasing prevalence of chronic disorders such as cancer in humans and increasing demand for personalized medicine. According to the World Health Organization (WHO), in 2020, cancer is amongst the critical conditions inflicting substantial disease burden, accounting for approximately 10 million deaths.

Similarly, as per the Cancer Statistics, in 2020, around 1.8 million new cancer cases were diagnosed in the U.S. alone. Therefore, the rise in the prevalence of such chronic human ailments is set to foster the demand for novel therapeutics and effective drugs. This demand in turn is expected to push the use of animal models in drug research & development, thereby propelling the segment outlook.

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The animal testing market caters to various users, including businesses, nonprofits, universities, and contract research organizations (CROs). In 2022, businesses were the biggest users of animal testing. This is because pharmaceutical and biotechnology companies spend a lot on research and development and rely heavily on animal models for their work. For example, a Johnson & Johnson report showed that in 2019, pharma companies' R&D budgets went up by 5%, with the top 11 companies spending a total of USD 77.6 billion. Animal models are crucial for helping decide whether or not to develop new drugs, from the early stages of testing to human trials. As governments and companies invest more in healthcare and people demand better treatments, the use of animal models is expected to keep growing.

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The animal model market in North America is poised to soar at an impressive 7.1% growth rate over the coming years. What's driving this growth? A surge in investments and a remarkable increase in clinical trials conducted right here in our backyard. The market is bustling with big names in the mice model industry, who are giving it a much-needed boost. And it's not just them—biomedical research is booming in the U.S., and both CROs (contract research organizations) and pharmaceutical giants are ramping up their preclinical activities in the region. As a result, the number of clinical trials is skyrocketing, and investors are pouring money into these studies. This growing demand for animal models is fueling the market's expansion, promising to make it a major player in the global animal model industry.

Animal Model Market Share

Major market players operating in the animal model market include

  • Charles River Laboratories, Inc.
  • Envigo
  • GenOway
  • Harbor BioMed
  • Trans Genic Inc.

These industry players majorly adopt various strategies including collaborations, acquisitions, mergers, and partnerships to create a global footprint and sustain market competition.

Animal Model Industry News

  • In March 2022, Charles River Laboratories signed an agreement with Hera Biolabs to breed, distribute, market, and sell Hera BioLabs' SRG rat to the global preclinical research community. This strategic move helped the company to diversify their product portfolio thereby increasing their geographical presence.
  • In October 2021, JACKSON LABORATORY announced the acquisition of Charles River Laboratories, Japan. The acquisition is intended to extend the firm’s animal model business, including advanced immunodeficient models and humanized mice along with expanding the firm’s presence in Japan. The company's animal model solutions will benefit from this launch that will help them boost the business development.

The animal model market research report includes an in-depth coverage of the industry with estimates & forecast in terms of revenue in USD from 2018 to 2032, for the following segments

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By Animal Type

 

  • Mice
  • Rats
  • Fish
  • Birds
  • Cattles
  • Pigs
  • Amphibians
  • Guinea Pigs
  • Dogs
  • Cats
  • Rabbits
  • Monkeys
  • Sheep
  • Hamsters
  • Other animal types

By Technology

  • CRISPR
  • Microinjection
  • Embryonic Stem Cell Injection
  • Nuclear Transfer
  • Other technologies

By Application

  • Research & Development
  • Infectious Disease
  • Immunological Diseases
  • Cancer
  • Cardiovascular Diseases
  • Diabetes
  • Genetic Diseases
  • Neurological Diseases
  • Obesity
  • NAFLD/NASH
  • Renal Disease
  • Diabetic Eye Disease
  • Fibrosis
  • Microbiome
  • Other Research & Development Applications 
  • Production and Quality Control
  • Academics
  • Preclinical Applications
  • Infectious Disease
  • Immunological Diseases
  • Cancer
  • Cardiovascular Diseases
  • Diabetes
  • Genetic Diseases
  • Neurological Diseases
  • Obesity
  • NAFLD/NASH
  • Renal Disease
  • Diabetic Eye Disease
  • Fibrosis
  • Microbiome
  • Other Preclinical Applications
  • Other Applications

By Use

  • Human
  • Veterinary

By End-use

  • Companies
  • Pharmaceutical
  • Biotechnology
  • Cosmetics
  • Other Companies 
  • Organizations
  • Government
  • Non-government
  • Academic and Research Institutes
  • Contract Research Organizations (CRO)

The above information is provided for the following regions and countries

  • North America
    • U.S.
    • Canada
  • Europe
    • Germany
    • UK
    • France
    • Spain
    • Italy
    • Switzerland
    • Netherlands
    • Czech Republic
    • Poland
    • Belgium
    • Finland
    • Hungary
    • Denmark
    • Ireland
    • Sweden
    • Rest of Europe
  • Asia Pacific
    • China
    • Japan
    • Australia
    • South Korea
    • New Zealand
    • Taiwan
    • Rest of Asia Pacific
  • Latin America
    • Brazil
    • Mexico
    • Argentina
    • Rest of Latin America
  • Middle East & Africa
    • South Africa
    • Saudi Arabia
    • UAE
    • Israel
    • Rest of MEA

 

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